Hidekazu Sakai
Overview
Explore the profile of Hidekazu Sakai including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
297
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0
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Recent Articles
1.
Wilson T, McLaughlin K, McEwan M, Sakai H, Rogers K, Redmond K, et al.
Cancer Res
. 2007 Jun;
67(12):5754-62.
PMID: 17575142
c-FLIP is an inhibitor of apoptosis mediated by the death receptors Fas, DR4, and DR5 and is expressed as long (c-FLIP(L)) and short (c-FLIP(S)) splice forms. We found that small...
2.
Rogers K, Thomas M, Galligan L, Wilson T, Allen W, Sakai H, et al.
Mol Cancer Ther
. 2007 May;
6(5):1544-51.
PMID: 17513603
Combination treatment regimens that include topoisomerase-II-targeted drugs, such as doxorubicin, are widely used in the treatment of breast cancer. Previously, we showed that IFN-gamma and doxorubicin cotreatment synergistically induced apoptosis...
3.
Sakai H, Jinawath A, Yamaoka S, Yuasa Y
Biochem Biophys Res Commun
. 2005 Jun;
333(4):1254-60.
PMID: 15979574
To clarify the mechanism underlying regulation of MUC6 expression, we isolated the 5' flanking region of the MUC6 gene (5'-MUC6). We determined the transcription start site of the MUC6 gene,...
4.
Yuasa Y, Nagasaki H, Akiyama Y, Sakai H, Nakajima T, Ohkura Y, et al.
Carcinogenesis
. 2004 Oct;
26(1):193-200.
PMID: 15498792
Epigenetic gene silencing through DNA methylation is one of the important steps in the mechanism underlying tumorigenesis, including in the stomach. Past lifestyle factors of cancer patients, such as intake...
5.
Li X, Eishi Y, Bai Y, Sakai H, Akiyama Y, Tani M, et al.
Int J Oncol
. 2004 Jan;
24(2):257-63.
PMID: 14719100
SOX2, a SRY-related HMG box protein, is thought to be an important transcription factor during organogenesis, including the stomach although the expression and function are unclear. We investigated SOX2 protein...
6.
Akiyama Y, Watkins N, Suzuki H, Jair K, van Engeland M, Esteller M, et al.
Mol Cell Biol
. 2003 Nov;
23(23):8429-39.
PMID: 14612389
The GATA family of transcription factors participates in gastrointestinal (GI) development. Increases in GATA-4 and -5 expression occur in differentiation and GATA-6 expression in proliferation in embryonic and adult settings....