Hideaki Takata
Overview
Explore the profile of Hideaki Takata including associated specialties, affiliations and a list of published articles.
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Articles
32
Citations
821
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Recent Articles
1.
CRISPR imaging reveals chromatin fluctuation at the centromere region related to cellular senescence
Takata H, Masuda Y, Ohmido N
Sci Rep
. 2023 Sep;
13(1):14609.
PMID: 37670098
The human genome is spatially and temporally organized in the nucleus as chromatin, and the dynamic structure of chromatin is closely related to genome functions. Cellular senescence characterized by an...
2.
Dwiranti A, Arifudin F, Takata H, Ohmido N, Fukui K
Microsc Res Tech
. 2020 Jul;
83(11):1411-1416.
PMID: 32648619
Divalent cations, mainly calcium and magnesium ions, are known to play a major role in the maintenance of chromosomes. The depletion of both ions using ethylenediaminetetraacetic acid (EDTA) results in...
3.
Wako T, Yoshida A, Kato J, Otsuka Y, Ogawa S, Kaneyoshi K, et al.
Sci Rep
. 2020 Jun;
10(1):8948.
PMID: 32488088
During cell division, mitotic chromosomes assemble and are equally distributed into two new daughter cells. The chromosome organisation of the two chromatids is essential for even distribution of genetic materials....
4.
Dwiranti A, Takata H, Fukui K
Microsc Microanal
. 2019 Apr;
25(3):817-821.
PMID: 30992092
The structural details of chromosomes have been of interest to researchers for many years, but how the metaphase chromosome is constructed remains unsolved. Divalent cations have been suggested to be...
5.
Takata H, Madung M, Katoh K, Fukui K
PLoS One
. 2018 Dec;
13(12):e0209614.
PMID: 30576375
Chromosome organization during cell division is achieved through the timely association of proteins with chromatin and is regulated by protein phosphorylation. Kinesin family member 4A (KIF4A) plays an important role...
6.
Poonperm R, Takata H, Uchiyama S, Fukui K
PLoS One
. 2017 Aug;
12(8):e0183298.
PMID: 28817632
Kinesin family member 4 (KIF4) and condensins I and II are essential chromosomal proteins for chromosome organization by locating primarily to the chromosome scaffold. However, the mechanism of how KIF4...
7.
Phengchat R, Takata H, Uchiyama S, Fukui K
Sci Rep
. 2017 Aug;
7(1):7335.
PMID: 28779172
The attachment of spindle fibres to the kinetochore is an important process that ensures successful completion of the cell division. The Ca concentration increases during the mitotic phase and contributes...
8.
Phengchat R, Takata H, Morii K, Inada N, Murakoshi H, Uchiyama S, et al.
Sci Rep
. 2016 Dec;
6:38281.
PMID: 27910894
Chromosome condensation is essential for the faithful transmission of genetic information to daughter cells during cell division. The depletion of chromosome scaffold proteins does not prevent chromosome condensation despite structural...
9.
Imai R, Komeda S, Shimura M, Tamura S, Matsuyama S, Nishimura K, et al.
Sci Rep
. 2016 Apr;
6:24712.
PMID: 27094881
Chromatin DNA must be read out for various cellular functions, and copied for the next cell division. These processes are targets of many anticancer agents. Platinum-based drugs, such as cisplatin,...
10.
Poonperm R, Takata H, Hamano T, Matsuda A, Uchiyama S, Hiraoka Y, et al.
Sci Rep
. 2015 Jul;
5:11916.
PMID: 26132639
Chromosome higher order structure has been an enigma for over a century. The most important structural finding has been the presence of a chromosome scaffold composed of non-histone proteins; so-called...