Kazuhiro Maeshima
Overview
Explore the profile of Kazuhiro Maeshima including associated specialties, affiliations and a list of published articles.
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Articles
79
Citations
3632
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Recent Articles
1.
Fujishiro S, Sasai M, Maeshima K
Curr Opin Struct Biol
. 2025 Feb;
91:103006.
PMID: 39983411
Negatively charged genomic DNA wraps around positively charged core histone octamers to form nucleosomes, which, along with proteins and RNAs, self-organize into chromatin within the nucleus. In eukaryotic cells, chromatin...
2.
Iida S, Ide S, Tamura S, Sasai M, Tani T, Goto T, et al.
Proc Natl Acad Sci U S A
. 2024 Aug;
121(36):e2403153121.
PMID: 39190347
Genomic information must be faithfully transmitted into two daughter cells during mitosis. To ensure the transmission process, interphase chromatin is further condensed into mitotic chromosomes. Although protein factors like condensins...
3.
Hibino K, Sakai Y, Tamura S, Takagi M, Minami K, Natsume T, et al.
Nat Commun
. 2024 Aug;
15(1):7152.
PMID: 39169041
For accurate mitotic cell division, replicated chromatin must be assembled into chromosomes and faithfully segregated into daughter cells. While protein factors like condensin play key roles in this process, it...
4.
Semeigazin A, Iida S, Minami K, Tamura S, Ide S, Higashi K, et al.
Histochem Cell Biol
. 2024 May;
162(1-2):23-40.
PMID: 38743310
Since Robert Feulgen first stained DNA in the cell, visualizing genome chromatin has been a central issue in cell biology to uncover how chromatin is organized and behaves in the...
5.
Otsuka A, Minami K, Higashi K, Kawaguchi A, Tamura S, Ide S, et al.
Chromosoma
. 2024 Feb;
133(2):135-148.
PMID: 38400910
In higher eukaryotic cells, a string of nucleosomes, where long genomic DNA is wrapped around core histones, are rather irregularly folded into a number of condensed chromatin domains, which have...
6.
Iida S, Ide S, Tamura S, Tani T, Goto T, Shribak M, et al.
bioRxiv
. 2023 Nov;
PMID: 37986866
Genomic information must be faithfully transmitted into two daughter cells during mitosis. To ensure the transmission process, interphase chromatin is further condensed into mitotic chromosomes. Although protein factors like condensins...
7.
Maeshima K, Iida S, Shimazoe M, Tamura S, Ide S
Trends Cell Biol
. 2023 Jun;
34(1):7-17.
PMID: 37385880
Genomic DNA is wrapped around a core histone octamer and forms a nucleosome. In higher eukaryotic cells, strings of nucleosomes are irregularly folded as chromatin domains that act as functional...
8.
Smallwood K, Watt K, Ide S, Baltrunaite K, Brunswick C, Inskeep K, et al.
Am J Hum Genet
. 2023 Apr;
110(5):809-825.
PMID: 37075751
Heterozygous pathogenic variants in POLR1A, which encodes the largest subunit of RNA Polymerase I, were previously identified as the cause of acrofacial dysostosis, Cincinnati-type. The predominant phenotypes observed in the...
9.
Nozaki T, Shinkai S, Ide S, Higashi K, Tamura S, Shimazoe M, et al.
Sci Adv
. 2023 Apr;
9(14):eadf1488.
PMID: 37018405
In eukaryotes, higher-order chromatin organization is spatiotemporally regulated as domains, for various cellular functions. However, their physical nature in living cells remains unclear (e.g., condensed domains or extended fiber loops;...
10.
Minami K, Iida S, Maeshima K
Enzymes
. 2022 Nov;
51:29-51.
PMID: 36336407
Genomic DNA is organized three-dimensionally in the nucleus as chromatin. Recent accumulating evidence has demonstrated that chromatin organizes into numerous dynamic domains in higher eukaryotic cells, which act as functional...