Hermann Pelzer
Overview
Explore the profile of Hermann Pelzer including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
78
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Recent Articles
1.
Boysen L, Viuff B, Landsy L, Lykkesfeldt J, Raymond J, Price S, et al.
Toxicol Pathol
. 2020 Apr;
48(4):570-585.
PMID: 32319353
Administration of human protein-based drugs to animals often leads to formation of antidrug antibodies (ADAs) that may form circulating immune complexes (CICs) with the dosed protein. Circulating immune complexes can...
2.
Almholt K, Hebsgaard J, Nansen A, Andersson C, Pass J, Rono B, et al.
J Immunol
. 2017 Dec;
200(3):957-965.
PMID: 29282305
Genetic absence of the urokinase-type plasminogen activator (uPA) reduces arthritis progression in the collagen-induced arthritis (CIA) mouse model to an extent just shy of disease abrogation, but this remarkable observation...
3.
Soendergaard C, Kvist P, Seidelin J, Pelzer H, Nielsen O
J Gastroenterol
. 2015 Dec;
51(8):796-807.
PMID: 26660730
Background: Subunit A of coagulation factor XIII (FXIII-A) is important for clot stability and acts in the subsequent wound healing process. Loss of plasma FXIII-A has been reported after surgery,...
4.
Andersson C, Kvist P, McElhinney K, Baylis R, Gram L, Pelzer H, et al.
PLoS One
. 2015 Jun;
10(6):e0128113.
PMID: 26098308
The thrombin-activated transglutaminase factor XIII (FXIII) that covalently crosslinks and stablizes provisional fibrin matrices is also thought to support endothelial and epithelial barrier function and to control inflammatory processes. Here,...
5.
Stennicke H, Kjalke M, Karpf D, Balling K, Johansen P, Elm T, et al.
Blood
. 2013 Jan;
121(11):2108-16.
PMID: 23335368
Frequent infusions of intravenous factor VIII (FVIII) are required to prevent bleeding associated with hemophilia A. To reduce the treatment burden, recombinant FVIII with a longer half-life was developed without...
6.
Agerso H, Kristensen N, Ostergaard H, Karpf D, Hermit M, Pelzer H, et al.
Eur J Pharm Sci
. 2011 Mar;
42(5):578-83.
PMID: 21382491
Aim: NN1731 is a recombinant activated factor VII (rFVIIa) analogue with enhanced activity. The objective of the present study was to evaluate the clearance mechanisms of rFVIIa and NN1731 after...
7.
Johansson L, Karpf D, Hansen L, Pelzer H, Persson E
Blood
. 2011 Jan;
117(12):3445-52.
PMID: 21252090
Coagulation factors VII (FVII), IX (FIX), X (FX), and protein C share the same domain organization but display very different plasma half-lives. It is plausible that the half-life is influenced...
8.
Petersen L, Karpf D, Agerso H, Hermit M, Pelzer H, Persson E, et al.
Br J Haematol
. 2010 Nov;
152(1):99-107.
PMID: 21083658
NN1731 is a recombinant activated factor VII (rFVIIa) analogue with increased intrinsic activity. This also applies to its reactivity towards antithrombin (AT), the role of which was investigated in a...