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Henry Mwandumba

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Articles 13
Citations 130
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Recent Articles
1.
Zumwinkel M, Chirambo A, Zahnle M, Burger M, Grieshober M, Romahn V, et al.
Infect Immun . 2024 Dec; 93(1):e0029724. PMID: 39660897
Protection against infections with intracellular bacteria requires the interaction of macrophages and T-lymphocytes, including CD8 T cells. Recently, the expression of natural killer cell receptors NKG2A and NKG2C was introduced...
2.
Mbangiwa T, Sturny-Leclere A, Lechiile K, Kajanga C, Boyer-Chammard T, Hoving J, et al.
Lancet Microbe . 2024 Feb; 5(3):e261-e271. PMID: 38342110
Background: HIV-associated cryptococcal meningitis is the second leading cause of AIDS-related deaths, with a 10-week mortality rate of 25-30%. Fungal load assessed by colony-forming unit (CFU) counts is used as...
3.
Howard A, Aston S, Gerada A, Reza N, Bincalar J, Mwandumba H, et al.
Lancet Digit Health . 2023 Dec; 6(1):e79-e86. PMID: 38123255
The proliferation of various forms of artificial intelligence (AI) brings many opportunities to improve health care. AI models can harness complex evolving data, inform and augment human actions, and learn...
4.
Gordon S, Sichone S, Chirwa A, Hazenberg P, Kafuko Z, Ferreira D, et al.
Wellcome Open Res . 2023 Jun; 8:71. PMID: 37007907
Tuberculosis (TB) remains a major challenge in many domains including diagnosis, pathogenesis, prevention, treatment, drug resistance and long-term protection of the public health by vaccination. A controlled human infection model...
5.
Anscombe C, Lissauer S, Thole H, Rylance J, Dula D, Menyere M, et al.
BMC Infect Dis . 2023 Feb; 23(1):79. PMID: 36750921
Background: Compared to the abundance of clinical and genomic information available on patients hospitalised with COVID-19 disease from high-income countries, there is a paucity of data from low-income countries. Our...
6.
Kelly C, Gurung R, Kamngona R, Sheha I, Chammudzi M, Jambo K, et al.
Wellcome Open Res . 2022 Oct; 6:264. PMID: 36300175
 We aim to investigate whether circulating microparticle (CMPs) subsets were raised amongst people presenting with a new diagnosis of HIV and advanced immune suppression in Malawi, and whether they associated...
7.
Anscombe C, Lissauer S, Thole H, Rylance J, Dula D, Menyere M, et al.
medRxiv . 2022 Jul; PMID: 35860218
Background: Compared to the abundance of clinical and genomic information available on patients hospitalised with COVID-19 disease from high-income countries, there is a paucity of data from low-income countries. Our...
8.
Kelly C, Tinago W, Alber D, Hunter P, Luckhurst N, Connolly J, et al.
PLoS One . 2021 Aug; 16(8):e0256576. PMID: 34432828
Background: Non-communicable diseases (NCDs) are increased amongst people living with HIV (PLWH) and are driven by persistent immune activation. The role of socioeconomic status (SES) in immune activation amongst PLWH...
9.
Kelly C, Tinago W, Alber D, Hunter P, Luckhurst N, Connolly J, et al.
Clin Infect Dis . 2020 Feb; 71(9):2389-2397. PMID: 32103268
Background: Inflammation drives vascular dysfunction in HIV, but in low-income settings causes of inflammation are multiple, and include infectious and environmental factors. We hypothesized that patients with advanced immunosuppression could...
10.
Peterson I, Ntsui N, Jambo K, Kelly C, Huwa J, Afran L, et al.
BMJ Open . 2019 Sep; 9(9):e025576. PMID: 31515413
Introduction: In Sub-Saharan Africa, the rising rates of cerebrovascular and cardiovascular diseases (CBD/CVD) are intersecting with an ageing HIV-infected population. The widespread use of antiretroviral therapy (ART) may confer an...