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Henry H Y Tong

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Articles 51
Citations 616
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Recent Articles
1.
Cheng S, Tong H, Zhang C, Jian L, Ji J, Li T, et al.
Brain Behav . 2025 Feb; 15(2):e70323. PMID: 39935140
Background And Aims: Adolescent major depressive disorder (MDD) is prevalent globally but often goes unnoticed due to differences in symptoms compared to adult criteria. Analyzing the brain from a network...
2.
Jiao F, Xu R, Luo Q, Li X, Tong H, Guo J
J Comput Aided Mol Des . 2025 Feb; 39(1):6. PMID: 39915349
Ceftaroline (CFT) effectively combats methicillin-resistant Staphylococcus aureus (MRSA) by binding to the allosteric site on penicillin-binding protein 2a (PBP2a) and activating allosteric signals that remotely open the active pocket. However,...
3.
Yan X, Zhu L, Li Q, Tian Y, Qiu J, Liu X, et al.
Int J Biol Macromol . 2025 Jan; 297:139820. PMID: 39805439
As a crucial drug target, KRAS can regulate most cellular processes involving guanosine triphosphate (GTP) hydrolysis. However, the mechanism of GTP hydrolysis has remained controversial over the past decades. Here,...
4.
Bao Y, Jia F, Geng Y, Song G, Xu R, Wang H, et al.
J Agric Food Chem . 2024 Dec; 73(1):189-201. PMID: 39688289
and are two subtypes of (Fo), a pathogenic filamentous fungus. Phenamacril (PHA), a -specific fungicide that targets myosin I, exhibits significant hyphal growth inhibition in but shows weak resistance in...
5.
Liu Y, Zou X, Tong H, Ji Y, Tan L, Hao J
STAR Protoc . 2024 Dec; 5(4):103476. PMID: 39661506
It is challenging to predict the immunotherapy outcome from the baseline status of patients with cancer. Here, we introduce a protocol for constructing an immunotherapy prediction model utilizing single-cell RNA...
6.
Qiu J, Yan X, Tian Y, Li Q, Liu X, Yang Y, et al.
Int J Mol Sci . 2024 Nov; 25(21). PMID: 39518938
The simultaneous use of two or more drugs in clinical treatment may raise the risk of a drug-drug interaction (DDI). DDI prediction is very important to avoid adverse drug events...
7.
Zhai X, Tong H, Lam C, Xing A, Sha Y, Luo G, et al.
Nat Hum Behav . 2024 Nov; 8(12):2392-2405. PMID: 39496771
Depression represents a significant global public health challenge, and marital status has been recognized as a potential risk factor. However, previous investigations of this association have primarily focused on Western...
8.
Zhao L, Liu B, Tong H, Yao X, Liu H, Zhang Q
Protein Sci . 2024 Sep; 33(10):e5166. PMID: 39291929
Mycobacterial membrane protein Large 3 (MmpL3) of Mycobacterium tuberculosis (Mtb) is crucial for the translocation of trehalose monomycolate (TMM) across the inner bacterial cell membrane, making it a promising target...
9.
Gong X, Li S, Huang J, Tan S, Zhang Q, Tian Y, et al.
Eur J Med Chem . 2024 Sep; 279:116812. PMID: 39241668
Leucine-rich repeat kinase 2 (LRRK2) has been reported to be associated with familial and idiopathic Parkinson's disease (PD) risk and is a promising target for drug discovery against PD. To...
10.
Zhang W, Zhai X, Zhang C, Cheng S, Zhang C, Bai J, et al.
Psychiatry Res Neuroimaging . 2024 Aug; 344:111862. PMID: 39153232
Puberty is a vulnerable period for the onset of major depressive disorder (MDD) due to considerable neurodevelopmental changes. Prior diffusion tensor imaging (DTI) studies in depressed youth have had heterogeneous...