Henry F McFarland
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Explore the profile of Henry F McFarland including associated specialties, affiliations and a list of published articles.
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31
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2853
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Recent Articles
1.
Neil S, Huh J, Baronas V, Li X, McFarland H, Cherukuri M, et al.
Brain Behav Immun
. 2017 Feb;
62:332-343.
PMID: 28238951
Therapies with both immunomodulatory and neuroprotective properties are thought to have the greatest promise in reducing the severity and progression of multiple sclerosis (MS). Several reactive oxygen (ROS) and reactive...
2.
Yuen T, Johnson K, Miron V, Zhao C, Quandt J, Harrisingh M, et al.
Brain
. 2013 Mar;
136(Pt 4):1035-47.
PMID: 23518706
The development of new regenerative therapies for multiple sclerosis is hindered by the lack of potential targets for enhancing remyelination. The study of naturally regenerative processes such as the innate...
3.
Quandt J, Huh J, Baig M, Yao K, Ito N, Bryant M, et al.
J Immunol
. 2012 Aug;
189(6):2897-908.
PMID: 22888134
Genetic susceptibility to multiple sclerosis (MS) has been linked to the HLA-DR15 haplotype consisting of DRB1*15:01(DR2b) and DRB5*01:01(DR2a) alleles. Given almost complete linkage disequilibrium of the two alleles, recent studies...
4.
Bagnato F, Salman Z, Kane R, Auh S, Cantor F, Ehrmantraut M, et al.
Mult Scler
. 2010 Aug;
16(10):1203-12.
PMID: 20699284
Background: Neocortical lesions (NLs) largely contribute to the pathology of multiple sclerosis (MS), although their relevance in patients' disability remains unknown. Objective: To assess the incidence of T(1) hypointense NLs...
5.
Bomboi G, Ikonomidou V, Pellegrini S, Stern S, Gallo A, Auh S, et al.
J Neuroimaging
. 2010 Jul;
21(2):e57-63.
PMID: 20626570
Background And Purpose: Using high-field magnetic resonance imaging (MRI), we investigated the relationships between white matter (WM) lesion volume (LV), normal-appearing WM (NAWM) normalized volume, WM-lesion and NAWM magnetization transfer...
6.
Polman C, Bertolotto A, Deisenhammer F, Giovannoni G, Hartung H, Hemmer B, et al.
Lancet Neurol
. 2010 Jul;
9(7):740-50.
PMID: 20610349
The identification of factors that can affect the efficacy of immunomodulatory drugs in relapsing-remitting multiple sclerosis (MS) is important. For the available interferon-beta products, neutralising antibodies (NAb) have been shown...
7.
Pellicano C, Gallo A, Li X, Ikonomidou V, Evangelou I, Ohayon J, et al.
Arch Neurol
. 2010 Apr;
67(4):447-53.
PMID: 20385911
Background: Fatigue is a common and disabling symptom of multiple sclerosis (MS). Previous studies reported that damage of the corticostriatothalamocortical circuit is critical in its occurrence. Objective: To investigate the...
8.
McFarland H
Ann Indian Acad Neurol
. 2010 Feb;
12(4):254-63.
PMID: 20182573
Magnetic Resonance Imaging (MRI) has brought in several benefits to the study of Multiple Sclerosis (MS). It provides accurate measurement of disease activity, facilitates precise diagnosis, and aid in the...
9.
McFarland H
Results Probl Cell Differ
. 2009 Dec;
51:287-301.
PMID: 19960380
Current multiple sclerosis (MS) is generally thought to consist of two general pathological processes; acute inflammation and degeneration. The relationship between these two components is not understood. What is clear,...
10.
Bielekova B, Richert N, Howard T, Packer A, Blevins G, Ohayon J, et al.
Mult Scler
. 2009 Sep;
15(10):1206-14.
PMID: 19776093
Rolipram, a prototypic phosphodiesterase-4 inhibitor, is highly effective in suppressing Th1 autoimmunity in multiple animal models, including experimental autoimmune encephalomyelitis. In addition, rolipram has been extensively studied as a potential...