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Henri J Tochon-Danguy

Explore the profile of Henri J Tochon-Danguy including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 239
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Recent Articles
1.
Huang Y, Poniger S, Tsai C, Tochon-Danguy H, Ackermann U, Yen R
Appl Radiat Isot . 2020 Mar; 158:108871. PMID: 32113705
Automated three-step two-pot production of no-carrier-added (NCA) [F]FDOPA was first implemented in the iPHASE FlexLab module. Decay-corrected radiochemical yield (RCY) of [F]FDOPA synthesized by this method was 10~14% (n = ...
2.
Laurens E, Yeoh S, Rigopoulos A, OKeefe G, Tochon-Danguy H, Chong L, et al.
J Labelled Comp Radiopharm . 2016 Jul; 59(10):416-23. PMID: 27435268
The significance of imaging hypoxia with the positron emission tomography ligand [(18) F]FMISO has been demonstrated in a variety of cancers. However, the slow kinetics of [(18) F]FMISO require a...
3.
Alt K, Paterson B, Westein E, Rudd S, Poniger S, Jagdale S, et al.
Angew Chem Int Ed Engl . 2015 May; 54(26):7515-9. PMID: 25962581
A unique two-step modular system for site-specific antibody modification and conjugation is reported. The first step of this approach uses enzymatic bioconjugation with the transpeptidase Sortase A for incorporation of...
4.
Alt K, Paterson B, Ardipradja K, Schieber C, Buncic G, Lim B, et al.
Mol Pharm . 2014 Jul; 11(8):2855-63. PMID: 24999533
Imaging of activated platelets using an activation specific anti-GPIIb/IIIa integrin single-chain antibody (scFvanti-LIBS) conjugated to a positron emitting copper-64 complex of a cage amine sarcophagine chelator (MeCOSar) is reported. This...
5.
Laurens E, Yeoh S, Rigopoulos A, Cao D, Cartwright G, OKeefe G, et al.
Nucl Med Biol . 2014 Apr; 41(5):419-25. PMID: 24767600
[¹⁸F]FMISO is the most widely validated PET radiotracer for imaging hypoxic tissue. However, as a result of the pharmacokinetics of [¹⁸F]FMISO a 2h wait between tracer administration and patient scanning...
6.
Ackermann U, Plougastel L, Wichmann C, Goh Y, Yeoh S, Poniger S, et al.
J Labelled Comp Radiopharm . 2014 Jan; 57(2):115-20. PMID: 24395455
Site-specific radiolabelling of peptides or antibodies using [(18) F]FBEM is often preferred over non-site-specific radiolabelling with [(18) F]SFB because it does not affect the affinity of the antibody to its...
7.
Connell T, Hayne D, Ackermann U, Tochon-Danguy H, White J, Donnelly P
J Labelled Comp Radiopharm . 2013 Dec; 57(4):262-9. PMID: 24327475
New 1,4-substituted pyridyl-1,2,3-triazole ligands with pendent phenyl isothiocyanate functional groups linked to the heterocycle through a short methylene or longer polyethylene glycol spacers were prepared and conjugated to a peptide...
8.
Laurens E, Yeoh S, Rigopoulos A, Cao D, Cartwright G, OKeefe G, et al.
Nucl Med Biol . 2012 Feb; 39(6):871-82. PMID: 22336372
The significance of imaging hypoxia with the PET ligand [(18)F]FMISO has been demonstrated in a variety of cancers. However, the slow kinetics of [(18)F]FMISO require a 2-h delay between tracer...
9.
Olver J, OKeefe G, Jones G, Burrows G, Tochon-Danguy H, Ackermann U, et al.
Psychiatry Res . 2010 Jun; 183(1):85-8. PMID: 20538439
Functional neuroimaging studies in patients with obsessive-compulsive disorder (OCD) suggest there is a hyperactivation of the anterior cingulate cortex (ACC) during provocation of symptoms and conflict-inhibition tasks. Since dopamine, acting...
10.
OKeefe G, Saunder T, Ng S, Ackerman U, Tochon-Danguy H, Chan J, et al.
J Nucl Med . 2009 Jan; 50(2):309-15. PMID: 19164222
Unlabelled: Beta-amyloid (Abeta) imaging has great potential to aid in the diagnosis of Alzheimer disease and the development of therapeutics. The radiation dosimetry of Abeta radioligands may influence their application;...