Heli Tiensuu
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Explore the profile of Heli Tiensuu including associated specialties, affiliations and a list of published articles.
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7
Citations
61
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Recent Articles
1.
Tiensuu H, Haapalainen A, Tissarinen P, Pasanen A, Hallman M, Ramet M
Placenta
. 2024 Aug;
155:60-69.
PMID: 39137705
Introduction: MicroRNAs regulate post-transcriptional gene expression. Their expression has been linked to many pregnancy complications, including preterm birth. Placental microRNA levels differ between preterm and term pregnancies. Not much is...
2.
Tissarinen P, Tiensuu H, Haapalainen A, Ronkainen E, Laatio L, Vaarasmaki M, et al.
Sci Rep
. 2024 May;
14(1):10819.
PMID: 38734716
Currently, there are no accurate means to predict spontaneous preterm birth (SPTB). Recently, we observed low expression of alpha-1 antitrypsin (AAT) in SPTB placentas. Present aim was to compare the...
3.
Pasanen A, Karjalainen M, Zhang G, Tiensuu H, Haapalainen A, Ojaniemi M, et al.
PLoS Genet
. 2023 Oct;
19(10):e1010982.
PMID: 37871108
Background: Preterm birth (<37 weeks of gestation) is a major cause of neonatal death and morbidity. Up to 40% of the variation in timing of birth results from genetic factors,...
4.
Tissarinen P, Tiensuu H, Haapalainen A, Maatta T, Ojaniemi M, Hallman M, et al.
Pediatr Res
. 2023 Feb;
94(2):520-529.
PMID: 36788289
Background: Specific heat shock proteins are associated with pregnancy complications, including spontaneous preterm birth (SPTB). Placental proteomics and whole exome sequencing recently suggested an association between heat shock protein HSPA5...
5.
Human placental proteomics and exon variant studies link AAT/SERPINA1 with spontaneous preterm birth
Tiensuu H, Haapalainen A, Tissarinen P, Pasanen A, Maatta T, Huusko J, et al.
BMC Med
. 2022 Apr;
20(1):141.
PMID: 35477570
Background: Preterm birth is defined as live birth before 37 completed weeks of pregnancy, and it is a major problem worldwide. The molecular mechanisms that lead to onset of spontaneous...
6.
Huusko J, Tiensuu H, Haapalainen A, Pasanen A, Tissarinen P, Karjalainen M, et al.
Sci Rep
. 2021 Aug;
11(1):17115.
PMID: 34429451
Heat shock proteins are involved in the response to stress including activation of the immune response. Elevated circulating heat shock proteins are associated with spontaneous preterm birth (SPTB). Intracellular heat...
7.
Tiensuu H, Haapalainen A, Karjalainen M, Pasanen A, Huusko J, Marttila R, et al.
PLoS Genet
. 2019 Jun;
15(6):e1008107.
PMID: 31194736
Spontaneous preterm birth (SPTB) is the leading cause of neonatal death and morbidity worldwide. Both maternal and fetal genetic factors likely contribute to SPTB. We performed a genome-wide association study...