Helene Guizouarn
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Explore the profile of Helene Guizouarn including associated specialties, affiliations and a list of published articles.
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38
Citations
584
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Recent Articles
1.
Jedele S, Allegrini B, Guizouarn H, Etchebest C
J Chem Inf Model
. 2025 Feb;
65(4):2116-2128.
PMID: 39928097
KCNN4 is a calcium (Ca)-activated potassium channel for which Ca sensitivity is conferred by calmodulin (CaM) that constitutively binds to the channel. Until the main part of the structure bound...
2.
Allegrini B, Mignotet M, Rapetti-Mauss R, Borgese F, Soriani O, Guizouarn H
J Biol Chem
. 2024 Dec;
301(2):108114.
PMID: 39716493
KCNN4, a Ca-activated K channel, is involved in various physiological and pathological processes. It is essential for epithelial transport, immune system, and other physiological mechanisms, but its activation is also...
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Allegrini B, NGuyen L, Mignotet M, Etchebest C, Fenneteau O, Platon J, et al.
Blood Cells Mol Dis
. 2023 Jul;
103:102780.
PMID: 37516005
We report here an instructive case referred at 16 months-old for exploration of hemolysis without anemia (compensated anemia with reticulocytosis). The biology tests confirmed the hemolysis with increased total and...
5.
Lohia R, Allegrini B, Berry L, Guizouarn H, Cerdan R, Abkarian M, et al.
Cell Mol Life Sci
. 2023 Apr;
80(5):124.
PMID: 37071200
An inherited gain-of-function variant (E756del) in the mechanosensitive cationic channel PIEZO1 was shown to confer a significant protection against severe malaria. Here, we demonstrate in vitro that human red blood...
6.
Rapetti-Mauss R, Nigri J, Berenguier C, Finetti P, Tubiana S, Labrum B, et al.
Gut
. 2023 Mar;
72(4):722-735.
PMID: 36882214
Objective: Intercellular communication within pancreatic ductal adenocarcinoma (PDAC) dramatically contributes to metastatic processes. The underlying mechanisms are poorly understood, resulting in a lack of targeted therapy to counteract stromal-induced cancer...
7.
Cannone S, Greco M, Carvalho T, Guizouarn H, Soriani O, Di Molfetta D, et al.
Cancers (Basel)
. 2022 Aug;
14(15).
PMID: 35954400
Background: Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest of all cancers, having one of the lowest five-year survival rates. One of its hallmarks is a dense desmoplastic stroma...
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9.
Yamaguchi Y, Allegrini B, Rapetti-Mauss R, Picard V, Garcon L, Kohl P, et al.
Front Physiol
. 2021 Nov;
12:736585.
PMID: 34737711
Hereditary Xerocytosis, a rare hemolytic anemia, is due to gain of function mutations in PIEZO1, a non-selective cation channel activated by mechanical stress. How these PIEZO1 mutations impair channel function...
10.
Livshits L, Barshtein G, Arbell D, Gural A, Levin C, Guizouarn H
Biomolecules
. 2021 Aug;
11(7).
PMID: 34356616
Red blood cell (RBC) transfusion is one of the most common therapeutic procedures in modern medicine. Although frequently lifesaving, it often has deleterious side effects. RBC quality is one of...