Helena Costa
Overview
Explore the profile of Helena Costa including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
383
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0
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Recent Articles
1.
Patel S, Karlsson M, Klahn J, Gambino Jr F, Costa H, McGuire K, et al.
SLAS Discov
. 2023 Dec;
29(2):100135.
PMID: 38101572
The cellular thermal shift assay (CETSA®) is a target engagement method widely used for preclinical characterization of small molecule compounds. CETSA® has been used for semi-quantitative readouts in whole blood...
2.
Househam J, Heide T, Cresswell G, Spiteri I, Kimberley C, Zapata L, et al.
Nature
. 2022 Oct;
611(7937):744-753.
PMID: 36289336
Genetic and epigenetic variation, together with transcriptional plasticity, contribute to intratumour heterogeneity. The interplay of these biological processes and their respective contributions to tumour evolution remain unknown. Here we show...
3.
Heide T, Househam J, Cresswell G, Spiteri I, Lynn C, Mossner M, et al.
Nature
. 2022 Oct;
611(7937):733-743.
PMID: 36289335
Colorectal malignancies are a leading cause of cancer-related deathand have undergone extensive genomic study. However, DNA mutations alone do not fully explain malignant transformation. Here we investigate the co-evolution of...
4.
Costa H, Hartasanchez R, Santos A, Camarao A, Cruz L, Nascimento M, et al.
Vet Parasitol Reg Stud Reports
. 2022 Feb;
28:100681.
PMID: 35115125
No study is currently available on the parasitofauna of the population of brown bears (Ursus arctos) inhabiting the Cantabrian Mountains in Spain. The aim of the present study was to...
5.
Golets A, Farias J, Pilati R, Costa H
Curr Psychol
. 2021 Sep;
42(3):2500-2513.
PMID: 34539156
Understanding tourist behavior during and after major tourism crises is essential to help destinations recover. The COVID-19 pandemic - a period of uncertainty and risk - makes it relevant to...
6.
Costa H, Klein J, Breines E, Nollens H, Matassa K, Garron M, et al.
Front Vet Sci
. 2021 Jun;
8:653094.
PMID: 34079832
Parapoxviruses cause nodular lesions on the skin and mucosal membranes of pinnipeds and infections by these viruses have been documented worldwide. Seal parapoxvirus is currently classified as a tentative species...
7.
Yaiw K, Mohammad A, Taher C, Cui H, Costa H, Kostopoulou O, et al.
Microorganisms
. 2021 Jun;
9(6).
PMID: 34070407
Human cytomegalovirus (HCMV) is an opportunistic pathogen that has been implicated in the pathogenesis of atherosclerosis. Endothelin-1 (ET-1), a potent vasoconstrictive peptide, is overexpressed and strongly associated with many vasculopathies....
8.
Wadsworth J, Joiner S, Linehan J, Jack K, Al-Doujaily H, Costa H, et al.
J Infect Dis
. 2021 Jan;
226(5):933-937.
PMID: 33502474
Chronic wasting disease (CWD) is the transmissible spongiform encephalopathy or prion disease affecting cervids. In 2016, the first cases of CWD were reported in Europe in Norwegian wild reindeer and...
9.
Luszczak S, Simpson B, Stopka-Farooqui U, Sathyadevan V, Carmona Echeverria L, Kumar C, et al.
Sci Rep
. 2020 Nov;
10(1):19870.
PMID: 33177621
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
10.
Luszczak S, Simpson B, Stopka-Farooqui U, Sathyadevan V, Carmona Echeverria L, Kumar C, et al.
Sci Rep
. 2020 Sep;
10(1):14380.
PMID: 32873828
PIM and PI3K/mTOR pathways are often dysregulated in prostate cancer, and may lead to decreased survival, increased metastasis and invasion. The pathways are heavily interconnected and act on a variety...