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Helen Wise

Explore the profile of Helen Wise including associated specialties, affiliations and a list of published articles. Areas
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Articles 47
Citations 1093
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Recent Articles
1.
Sharp C, Thompson B, Nash T, Diebold O, Pinto R, Thorley L, et al.
PLoS Pathog . 2023 May; 19(5):e1011357. PMID: 37146066
Synonymous recoding of RNA virus genomes is a promising approach for generating attenuated viruses to use as vaccines. Problematically, recoding typically hinders virus growth, but this may be rectified using...
2.
Muecksch F, Wise H, Templeton K, Batchelor B, Squires M, McCance K, et al.
Lancet Microbe . 2022 May; 3(7):e493-e502. PMID: 35636436
Background: Serological assays are being used to monitor antibody responses in individuals who had SARS-CoV-2 infection and those who received a COVID-19 vaccine. We aimed to determine whether such assays...
3.
McCance K, Wise H, Simpson J, Batchelor B, Hale H, McDonald L, et al.
PLoS One . 2022 Mar; 17(3):e0266086. PMID: 35358263
SARS-CoV-2 antibody tests have been marketed to diagnose previous SARS-CoV-2 infection and as a test of immune status. There is a lack of evidence on the performance and clinical utility...
4.
McDonald L, Wise H, Muecksch F, Poston D, Mavin S, Templeton K, et al.
J Clin Virol Plus . 2022 Mar; 1(3):100028. PMID: 35262014
Background: Sero-surveillance of SARS-CoV-2 is crucial to monitoring levels of population exposure and informing public health responses, but may be influenced by variability in performance between available assays. Methods: Five...
5.
Williams T, Wastnedge E, McAllister G, Bhatia R, Cuschieri K, Kefala K, et al.
Wellcome Open Res . 2022 Feb; 5:254. PMID: 35169637
This study aimed to determine the sensitivity and specificity of reverse transcription PCR (RT-PCR) testing of upper respiratory tract samples from hospitalised patients with coronavirus disease 2019 (COVID-19), compared to...
6.
Squires M, Wise H, Holmes H, Hadfield K
Ann Clin Biochem . 2021 Aug; 58(6):653-656. PMID: 34463152
Background: Spuriously high results using the Abbott Architect enzymatic creatinine assay were noted to be particularly associated with very small sample volumes. This led us to query the effect of...
7.
Muecksch F, Wise H, Templeton K, Batchelor B, Squires M, McCance K, et al.
medRxiv . 2021 Jul; PMID: 34268524
Background: Serological assays are being deployed to monitor antibody responses in SARS-CoV-2 convalescents and vaccine recipients. There is a need to determine whether such assays can predict immunity, as antibody...
8.
Poston D, Weisblum Y, Wise H, Templeton K, Jenks S, Hatziioannou T, et al.
Clin Infect Dis . 2020 Dec; 73(5):e1208-e1211. PMID: 33270134
Cross-reactive immune responses elicited by seasonal coronaviruses might affect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) susceptibility and disease outcomes. We measured neutralizing activity against SARS-CoV-2 in prepandemic sera from...
9.
Muecksch F, Wise H, Batchelor B, Squires M, Semple E, Richardson C, et al.
J Infect Dis . 2020 Nov; 223(3):389-398. PMID: 33140086
Background: Understanding the longitudinal trajectory of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies is crucial for diagnosis of prior infection and predicting future immunity. Methods: We conducted a longitudinal...
10.
Poston D, Weisblum Y, Wise H, Templeton K, Jenks S, Hatziioannou T, et al.
medRxiv . 2020 Oct; PMID: 33052353
Cross-reactive immune responses elicited by seasonal coronaviruses might impact SARS-CoV-2 susceptibility and disease outcomes. We measured neutralizing activity against SARS-CoV-2 in pre-pandemic sera from patients with prior PCR-confirmed seasonal coronavirus...