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Helen L Mitchell

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Articles 11
Citations 226
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Recent Articles
1.
Ngo S, Oxley E, Ghisi M, Garwood M, McKenzie M, Mitchell H, et al.
Nat Commun . 2021 Nov; 12(1):6546. PMID: 34764270
Acute myeloid leukemia (AML) is a malignancy of immature progenitor cells. AML differentiation therapies trigger leukemia maturation and can induce remission, but relapse is prevalent and its cellular origin is...
2.
Fernando J, Butler C, Adams G, Mitchell H, Dashper S, Escobar K, et al.
J Dent . 2019 Nov; 91:103225. PMID: 31693918
Objectives: To determine if chewing gum containing casein phosphopeptide stabilised amorphous calcium phosphate (CPP-ACP) promoted an increase in the abundance of Streptococcus sanguinis and other species associated with dental health...
3.
Dashper S, Mitchell H, Seers C, Gladman S, Seemann T, Bulach D, et al.
Front Microbiol . 2017 Feb; 8:48. PMID: 28184216
is a keystone pathogen of chronic periodontitis. The virulence of is reported to be strain related and there are currently a number of strain typing schemes based on variation in...
4.
Lenzo J, OBrien-Simpson N, Orth R, Mitchell H, Dashper S, Reynolds E
Infect Immun . 2016 Jun; 84(9):2575-85. PMID: 27354442
Periodontitis is a significant problem in companion animals, and yet little is known about the disease-associated microbiota. A major virulence factor for the human periodontal pathogen Porphyromonas gingivalis is the...
5.
Butler C, Dashper S, Zhang L, Seers C, Mitchell H, Catmull D, et al.
PLoS One . 2014 Nov; 9(11):e111168. PMID: 25375181
Porphyromonas gingivalis is a Gram-negative pathogen associated with the biofilm-mediated disease chronic periodontitis. P. gingivalis biofilm formation is dependent on environmental heme for which P. gingivalis has an obligate requirement...
6.
Tan K, Seers C, Dashper S, Mitchell H, Pyke J, Meuric V, et al.
PLoS Pathog . 2014 Mar; 10(3):e1003955. PMID: 24603978
Porphyromonas gingivalis and Treponema denticola are strongly associated with chronic periodontitis. These bacteria have been co-localized in subgingival plaque and demonstrated to exhibit symbiosis in growth in vitro and synergistic...
7.
Zainal-Abidin Z, Veith P, Dashper S, Zhu Y, Catmull D, Chen Y, et al.
J Proteome Res . 2012 Jul; 11(9):4449-64. PMID: 22808953
Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia exist in a polymicrobial biofilm associated with chronic periodontitis. The aim of this study was to culture these three species as a polymicrobial...
8.
Mitchell H, Aggett P, Richardson D, Stowell J
Br J Nutr . 2010 Sep; 105(2):322-8. PMID: 20860884
The present report summarises a meeting held by the Food & Health Forum at the Royal Society of Medicine, London, on 27 May 2010. The objective of the meeting was...
9.
Mitchell H, Dashper S, Catmull D, Paolini R, Cleal S, Slakeski N, et al.
Microbiology (Reading) . 2009 Dec; 156(Pt 3):774-788. PMID: 20007650
Treponema denticola is an oral spirochaete that has been strongly associated with chronic periodontitis. The bacterium exists as part of a dense biofilm (subgingival dental plaque) accreted to the tooth....
10.
Dashper S, Ang C, Veith P, Mitchell H, Lo A, Seers C, et al.
J Bacteriol . 2008 Nov; 191(3):1044-55. PMID: 19028886
Porphyromonas gingivalis is an anaerobic, asaccharolytic, gram-negative bacterium that has essential requirements for both iron and protoporphyrin IX, which it preferentially obtains as heme. A combination of large-scale quantitative proteomic...