Heinz Feldmann
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Explore the profile of Heinz Feldmann including associated specialties, affiliations and a list of published articles.
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475
Citations
21011
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Recent Articles
31.
Fletcher P, Feldmann F, Takada A, Crossland N, Hume A, Albarino C, et al.
J Infect Dis
. 2023 Jun;
228(Suppl 7):S548-S553.
PMID: 37352146
Type I interferon receptor knockout (IFNAR-/-) mice are not able to generate a complete innate immune response; therefore, these mice are often considered to assess the pathogenicity of emerging viruses....
32.
Mehedi M, Ricklefs S, Takada A, Sturdevant D, Porcella S, Marzi A, et al.
J Infect Dis
. 2023 Jun;
228(Suppl 7):S498-S507.
PMID: 37348869
RNA editing has been discovered as an essential mechanism for the transcription of the glycoprotein (GP) gene of Ebola virus but not Marburg virus. We developed a rapid transcript quantification...
33.
Marzi A, Feldmann F, ODonnell K, Hanley P, Messaoudi I, Feldmann H
J Infect Dis
. 2023 Jun;
228(Suppl 7):S671-S676.
PMID: 37290042
Ebola virus (EBOV) and Marburg virus (MARV) made headlines in the past decade, causing outbreaks of human disease in previously nonendemic yet overlapping areas. While EBOV outbreaks can be mitigated...
34.
ODonnell K, Callison J, Feldmann H, Hoenen T, Marzi A
J Infect Dis
. 2023 May;
228(Suppl 7):S677-S681.
PMID: 37186162
Although significant progress has been made in the development of therapeutics against Ebola virus (EBOV), we sought to expand upon existing strategies and combine an RNA interference-based intervention with the...
35.
36.
Li F, Carpentier K, Hawman D, Lucas C, Ander S, Feldmann H, et al.
Cell Rep
. 2023 Apr;
42(5):112418.
PMID: 37083332
Arboviruses are public health threats that cause explosive outbreaks. Major determinants of arbovirus transmission, geographic spread, and pathogenesis are the magnitude and duration of viremia in vertebrate hosts. Previously, we...
37.
OConnor M, Hawman D, Meade-White K, Leventhal S, Song W, Randall S, et al.
PLoS Pathog
. 2023 Apr;
19(4):e1011298.
PMID: 37075079
The global SARS-CoV-2 pandemic prompted rapid development of COVID-19 vaccines. Although several vaccines have received emergency approval through various public health agencies, the SARS-CoV-2 pandemic continues. Emergent variants of concern,...
38.
Hawman D, Feldmann H
Nat Rev Microbiol
. 2023 Mar;
21(7):463-477.
PMID: 36918725
Crimean-Congo haemorrhagic fever (CCHF) is a severe tick-borne illness with a wide geographical distribution and case fatality rates of 30% or higher. Caused by infection with the CCHF virus (CCHFV),...
39.
Marzi A, Fletcher P, Feldmann F, Saturday G, Hanley P, Feldmann H
Lancet Microbe
. 2023 Feb;
4(3):e171-e178.
PMID: 36739878
Background: The recent Sudan virus (SUDV) outbreak in Uganda highlights the need for rapid response capabilities, including development of vaccines against emerging viruses with high public health impact. We aimed...
40.
Rosenke K, Lewis M, Feldmann F, Bohrnsen E, Schwarz B, Okumura A, et al.
JCI Insight
. 2022 Dec;
8(4).
PMID: 36574296
The periodic emergence of SARS-CoV-2 variants of concern (VOCs) with unpredictable clinical severity and ability to escape preexisting immunity emphasizes the continued need for antiviral interventions. Two small molecule inhibitors,...