Heike M Hermanns
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Explore the profile of Heike M Hermanns including associated specialties, affiliations and a list of published articles.
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53
Citations
2685
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Recent Articles
1.
Wagner J, Vredevoogd D, Yu X, Lu D, Peeper D, Hermanns H, et al.
Cell Death Dis
. 2025 Jan;
16(1):35.
PMID: 39837830
This study suggests a modified model of TNFR1-induced complex I-mediated NFκB signaling. Evaluation of a panel of five tumor cell lines (HCT116-PIK3CAmut, SK-MEL-23, HeLa-RIPK3, HT29, D10) with TRAF2 knockout revealed...
2.
Schafer S, Gogiraju R, Rosch M, Kerstan Y, Beck L, Garbisch J, et al.
Arterioscler Thromb Vasc Biol
. 2024 Jun;
44(8):1852-1872.
PMID: 38868941
Background: Atherosclerosis is driven by the infiltration of the arterial intima by diverse immune cells and smooth muscle cells (SMCs). CD8 T cells promote lesion growth during atherosclerotic lesion development,...
3.
Butt E, Gunder T, Sturzebecher P, Kowalski I, Schneider P, Buschmann N, et al.
Am J Physiol Gastrointest Liver Physiol
. 2024 May;
327(1):G25-G35.
PMID: 38713618
Cholesterol is essential for the stability and architecture of the plasma membrane and a precursor of bile acids and steroid hormones in mammals. Excess dietary cholesterol uptake leads to hypercholesterolemia...
4.
Burkard P, Schonhart C, Vogtle T, Kohler D, Tang L, Johnson D, et al.
Blood
. 2023 Jul;
142(17):1463-1477.
PMID: 37441848
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are associated with high morbidity and mortality. Excessive neutrophil infiltration into the pulmonary airspace is the main cause for the...
5.
Elgheznawy A, Oftering P, Englert M, Mott K, Kaiser F, Kusch C, et al.
Front Immunol
. 2023 Jun;
14:1197894.
PMID: 37359521
Zinc (Zn) is considered as important mediator of immune cell function, thrombosis and haemostasis. However, our understanding of the transport mechanisms that regulate Zn homeostasis in platelets is limited. Zn...
6.
Schanbacher C, Hermanns H, Lorenz K, Wajant H, Lang I
Biomedicines
. 2023 Feb;
11(2).
PMID: 36831095
Adiponectin and the other 15 members of the complement 1q (C1q)/tumor necrosis factor (TNF)-related protein (CTRP) family are secreted proteins composed of an N-terminal variable domain followed by a stalk...
7.
Alonso-Pena M, Espinosa-Escudero R, Hermanns H, Briz O, Herranz J, Garcia-Ruiz C, et al.
Cells
. 2022 Dec;
11(24).
PMID: 36552746
Bile acid (BA) synthesis from cholesterol by hepatocytes is inhibited by inflammatory cytokines. Whether liver inflammation also affects BA side chain shortening and conjugation was investigated. In human liver cell...
8.
Cyran L, Serfling J, Kirschner L, Raifer H, Lohoff M, Hermanns H, et al.
Eur J Immunol
. 2022 Mar;
52(12):1946-1960.
PMID: 35357005
The development of two conventional dendritic cells (DC) subsets (cDC1 and cDC2) and the plasmacytoid DC (pDC) in vivo and in cultures of bone marrow (BM) cells is mediated by...
9.
Heib T, Hermanns H, Manukjan G, Englert M, Kusch C, Becker I, et al.
Cell Rep
. 2021 May;
35(6):109102.
PMID: 33979620
Megakaryocytes (MKs), the precursors of blood platelets, are large, polyploid cells residing mainly in the bone marrow. We have previously shown that balanced signaling of the Rho GTPases RhoA and...
10.
Thiem A, Hesbacher S, Kneitz H, Di Primio T, Heppt M, Hermanns H, et al.
J Exp Clin Cancer Res
. 2019 Sep;
38(1):397.
PMID: 31506076
Background: Immune checkpoint inhibition and in particular anti-PD-1 immunotherapy have revolutionized the treatment of advanced melanoma. In this regard, higher tumoral PD-L1 protein (gene name: CD274) expression is associated with...