Heike Kunze-Schumacher
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Explore the profile of Heike Kunze-Schumacher including associated specialties, affiliations and a list of published articles.
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19
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721
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Recent Articles
1.
Kunze-Schumacher H, Verheyden N, Grewers Z, Meyer-Hermann M, Greiff V, Robert P, et al.
Cell Rep
. 2025 Jan;
44(1):115132.
PMID: 39756036
Control of cell proliferation is critical for the lymphocyte life cycle. However, little is known about how stage-specific alterations in cell cycle behavior drive proliferation dynamics during T cell development....
2.
Cossarizza A, Chang H, Radbruch A, Abrignani S, Addo R, Akdis M, et al.
Eur J Immunol
. 2021 Dec;
51(12):2708-3145.
PMID: 34910301
The third edition of Flow Cytometry Guidelines provides the key aspects to consider when performing flow cytometry experiments and includes comprehensive sections describing phenotypes and functional assays of all major...
3.
Robert P, Kunze-Schumacher H, Greiff V, Krueger A
Entropy (Basel)
. 2021 Apr;
23(4).
PMID: 33918050
The thymus hosts the development of a specific type of adaptive immune cells called T cells. T cells orchestrate the adaptive immune response through recognition of antigen by the highly...
4.
Meyer A, Herkt S, Kunze-Schumacher H, Kohrs N, Ringleb J, Schneider L, et al.
Sci Rep
. 2020 Dec;
10(1):21438.
PMID: 33293632
A network of gene regulatory factors such as transcription factors and microRNAs establish and maintain gene expression patterns during hematopoiesis. In this network, transcription factors regulate each other and are...
5.
Kunze-Schumacher H, Krueger A
Front Immunol
. 2020 Oct;
11:2185.
PMID: 33013919
MicroRNAs (miRNAs) have emerged as critical posttranscriptional regulators of the immune system, including function and development of regulatory T (Treg) cells. Although this critical role has been firmly demonstrated through...
6.
Cossarizza A, Chang H, Radbruch A, Acs A, Adam D, Adam-Klages S, et al.
Eur J Immunol
. 2019 Oct;
49(10):1457-1973.
PMID: 31633216
These guidelines are a consensus work of a considerable number of members of the immunology and flow cytometry community. They provide the theory and key practical aspects of flow cytometry...
7.
Simper G, Graser L, Celik A, Kuhn J, Kunze-Schumacher H, Ho G, et al.
Pharmaceutics
. 2019 Oct;
11(10).
PMID: 31618895
Drug hypersensitivity reactions that resemble acute immune reactions are linked to certain human leucocyte antigen (HLA) alleles. Severe and life-threatening Stevens Johnson Syndrome and Toxic Epidermal Necrolysis following treatment with...
8.
Pump W, Schulz R, Huyton T, Kunze-Schumacher H, Martens J, Ho G, et al.
HLA
. 2019 Mar;
94(1):25-38.
PMID: 30912293
T-cell receptors possess the unique ability to survey and respond to their permanently modified ligands, self HLA-I molecules bound to non-self peptides of various origin. This highly specific immune function...
9.
Lyszkiewicz M, Winter S, Witzlau K, Fohse L, Brownlie R, Puchalka J, et al.
PLoS Biol
. 2019 Mar;
17(3):e2006716.
PMID: 30856173
The interdependence of selective cues during development of regulatory T cells (Treg cells) in the thymus and their suppressive function remains incompletely understood. Here, we analyzed this interdependence by taking...
10.
Brune T, Kunze-Schumacher H, Kolling R
Curr Genet
. 2018 Dec;
65(2):607-619.
PMID: 30506264
Here, we examine the genetic interactions between ESCRT-III mutations in the yeast Saccharomyces cerevisiae. From the obtained interaction network, we make predictions about alternative ESCRT-III complexes. By the successful generation...