Heidie Huyck
Overview
Explore the profile of Heidie Huyck including associated specialties, affiliations and a list of published articles.
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12
Citations
439
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Recent Articles
1.
Velickovic D, Purkerson J, Bhotika H, Huyck H, Clair G, Pryhuber G, et al.
bioRxiv
. 2024 Oct;
PMID: 39416038
-linked glycosylation, the major post-translational modification of cellular proteins, is important for proper lung functioning, serving to fold, traffic, and stabilize protein structures and to mediate various cell-cell recognition events....
2.
McDavid A, Laniewski N, Grier A, Gill A, Kessler H, Huyck H, et al.
iScience
. 2022 Mar;
25(4):104007.
PMID: 35310935
Neonatal immune-microbiota co-development is poorly understood, yet age-appropriate recognition of - and response to - pathogens and commensal microbiota is critical to health. In this longitudinal study of 148 preterm...
3.
Wang A, Chiou J, Poirion O, Buchanan J, Valdez M, Verheyden J, et al.
Elife
. 2020 Nov;
9.
PMID: 33164753
Respiratory failure associated with COVID-19 has placed focus on the lungs. Here, we present single-nucleus accessible chromatin profiles of 90,980 nuclei and matched single-nucleus transcriptomes of 46,500 nuclei in non-diseased...
4.
Wang Q, Bhattacharya S, Mereness J, Anderson C, Lillis J, Misra R, et al.
Pediatr Res
. 2019 Feb;
87(3):511-517.
PMID: 30776794
Background: Current in vitro human lung epithelial cell models derived from adult tissues may not accurately represent all attributes that define homeostatic and disease mechanisms relevant to the pediatric lung....
5.
Grier A, McDavid A, Wang B, Qiu X, Java J, Bandyopadhyay S, et al.
Microbiome
. 2018 Oct;
6(1):193.
PMID: 30367675
Background: Postnatal development of early life microbiota influences immunity, metabolism, neurodevelopment, and infant health. Microbiome development occurs at multiple body sites, with distinct community compositions and functions. Associations between microbiota...
6.
Scheible K, Emo J, Laniewski N, Baran A, Peterson D, Holden-Wiltse J, et al.
JCI Insight
. 2018 Feb;
3(4).
PMID: 29467329
The inverse relationship between gestational age at birth and postviral respiratory morbidity suggests that infants born preterm (PT) may miss a critical developmental window of T cell maturation. Despite a...
7.
Grier A, Qiu X, Bandyopadhyay S, Holden-Wiltse J, Kessler H, Gill A, et al.
Microbiome
. 2017 Dec;
5(1):158.
PMID: 29228972
Background: Identification of factors that influence the neonatal gut microbiome is urgently needed to guide clinical practices that support growth of healthy preterm infants. Here, we examined the influence of...
8.
Scheible K, Emo J, Yang H, Holden-Wiltse J, Straw A, Huyck H, et al.
Clin Immunol
. 2015 Aug;
161(2):65-74.
PMID: 26232733
Homeostatic T cell proliferation is more robust during human fetal development. In order to understand the relative effect of normal fetal homeostasis and perinatal exposures on CD8+ T cell behavior...
9.
Misra R, Shah S, Fowell D, Wang H, Scheible K, Misra S, et al.
Hum Immunol
. 2015 Mar;
76(5):329-338.
PMID: 25797206
Background: Chorioamnionitis (CA) is associated with premature delivery and bronchopulmonary dysplasia (BPD). We hypothesize that preterm infants exposed to CA have reduced suppressive regulatory T cells (Treg) and increased non-regulatory...
10.
Saperstein S, Huyck H, Kimball E, Johnston C, Finkelstein J, Pryhuber G
Mediators Inflamm
. 2009 Nov;
2009:958658.
PMID: 19901996
We determined the role of interleukin-1beta (IL-1beta) signaling on tumor necrosis factor alpha-induced (TNF-alpha) lung neutrophil influx as well as neutrophil chemoattractant macrophage inflammatory protein (MIP-2) and KC and soluble...