Heidi Ulrichs
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Explore the profile of Heidi Ulrichs including associated specialties, affiliations and a list of published articles.
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9
Citations
46
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Recent Articles
1.
Ulrichs H, Shekhar S
Curr Opin Cell Biol
. 2025 Jan;
92:102459.
PMID: 39765045
Twinfilin is an evolutionarily conserved actin-binding protein initially mischaracterized as a tyrosine kinase but later recognized as a key regulator of cellular actin dynamics. As a member of the ADF-H...
2.
Ulrichs H, Shekhar S
J Cell Biol
. 2024 Jun;
223(7).
PMID: 38832903
Profilin binds microtubules in vitro. However, a new study by Vitriol and colleagues (https://doi.org/10.1083/jcb.202309097) now suggests that effects of profilin on microtubule dynamics in cells are indirect and result from...
3.
Towsif E, Miller B, Ulrichs H, Shekhar S
Eur J Cell Biol
. 2024 May;
103(2):151423.
PMID: 38796920
Intracellular actin networks assemble through the addition of ATP-actin subunits at the growing barbed ends of actin filaments. This is followed by "aging" of the filament via ATP hydrolysis and...
4.
Towsif E, Miller B, Ulrichs H, Shekhar S
bioRxiv
. 2024 Apr;
PMID: 38659736
Intracellular actin networks assemble through the addition of ATP-actin subunits at the growing barbed ends of actin filaments. This is followed by "aging" of the filament via ATP hydrolysis and...
5.
Dookwah M, Wagner S, Ishihara M, Yu S, Ulrichs H, Kulik M, et al.
Hum Mol Genet
. 2023 Sep;
32(24):3323-3341.
PMID: 37676252
GM3 Synthase Deficiency (GM3SD) is a neurodevelopmental disorder resulting from pathogenic variants in the ST3GAL5 gene, which encodes GM3 synthase, a glycosphingolipid (GSL)-specific sialyltransferase. This enzyme adds a sialic acid...
6.
Ulrichs H, Gaska I, Shekhar S
Nat Commun
. 2023 Jul;
14(1):3981.
PMID: 37414761
Cells control actin assembly by regulating reactions at actin filament barbed ends. Formins accelerate elongation, capping protein (CP) arrests growth and twinfilin promotes depolymerization at barbed ends. How these distinct...
7.
Ulrichs H, Gaska I, Shekhar S
bioRxiv
. 2023 May;
PMID: 37163095
Living cells assemble their actin networks by regulating reactions at the barbed end of actin filaments. Formins accelerate elongation, capping protein (CP) arrests growth and twinfilin promotes depolymerization at barbed...
8.
Kudryashova E, Ankita , Ulrichs H, Shekhar S, Kudryashov D
Sci Adv
. 2022 Nov;
8(46):eadc9239.
PMID: 36399577
According to the cellular actin dynamics paradigm, filaments grow at their barbed ends and depolymerize predominantly from their pointed ends to form polar structures and do productive work. We show...
9.
Saito-Diaz K, Street J, Ulrichs H, Zeltner N
Stem Cell Reports
. 2021 Feb;
16(3):446-457.
PMID: 33545066
The three peripheral sensory neuron (SN) subtypes, nociceptors, mechanoreceptors, and proprioceptors, localize to dorsal root ganglia and convey sensations such as pain, temperature, pressure, and limb movement/position. Despite previous reports,...