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Hedong Zhang

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Articles 37
Citations 152
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Recent Articles
1.
Zhang H, Zhong M, Hu S, Tan L, Peng L, Xie X, et al.
Eur J Med Res . 2025 Mar; 30(1):167. PMID: 40082914
Objective: To investigate the clinical characteristics, diagnosis and treatment of tuberculosis infection after deceased donor kidney transplantation and to analyze the risk factors and prognosis of tuberculosis infection through a...
2.
Zeng Y, Yuan W, Feng C, Peng L, Xie X, Peng F, et al.
Transpl Immunol . 2025 Feb; 89:102183. PMID: 39892762
Background: Sepsis-induced acute kidney injury (AKI) is a severe condition characterized by dysregulation of pro- and anti-inflammatory responses. Targeting macrophage polarization between pro-inflammatory M1 and anti-inflammatory M2 cells offers a...
3.
Zhu Y, Zheng X, Chen C, Xu Y, Fan Y, Tang Z, et al.
J Leukoc Biol . 2025 Jan; PMID: 39835675
Macrophages play a crucial role in the immune response during allograft rejection in organ transplantation. Therefore, our study aimed to explore the genomic features of macrophages in mouse heart transplants...
4.
Chen C, Feng C, Luo Q, Zeng Y, Yuan W, Cui Y, et al.
Life Sci . 2024 Aug; 354:122945. PMID: 39127319
Renal fibrosis is the common final pathway of progressive renal diseases, in which the macrophages play an important role. ELISA was used to detect CD5 antigen-like (CD5L) in serum samples...
5.
Cui Y, Chen C, Tang Z, Yuan W, Yue K, Cui P, et al.
Cell Death Dis . 2024 Jun; 15(6):401. PMID: 38849370
The triggering receptor expressed on myeloid cells 2 (TREM2) is an immune receptor that affects cellular phenotypes by modulating phagocytosis and metabolism, promoting cell survival, and counteracting inflammation. Its role...
6.
Yuan W, Zhang H, Peng L, Chen C, Feng C, Tang Z, et al.
Chin Med J (Engl) . 2024 May; PMID: 38811343
Background: T cell dysfunction, which includes exhaustion, anergy, and senescence, is a distinct T cell differentiation state that occurs after antigen exposure. Although T cell dysfunction has been a cornerstone...
7.
Fan Y, Xu Y, Huo Z, Zhang H, Peng L, Jiang X, et al.
Chin Med J (Engl) . 2024 May; 137(14):1663-1673. PMID: 38809056
Triggering receptor expressed on myeloid cells-1 (TREM-1) is a member of the immunoglobulin superfamily. As an amplifier of the inflammatory response, TREM-1 is mainly involved in the production of inflammatory...
8.
Tang Z, Feng C, Li Y, Li T, Zhang H, Zeng Y, et al.
Zhong Nan Da Xue Xue Bao Yi Xue Ban . 2024 May; 49(2):220-235. PMID: 38755718
Objectives: The mouse kidney transplantation model presents challenges in terms of surgical difficulty and low success rate, making it difficult to master. This study aims to provide a crucial model...
9.
Gao S, Zhou M, Zhang H, Tang Z
Curr Med Chem . 2024 Feb; 32(4):825-829. PMID: 38362687
Wilson's Disease (WD), a genetic metabolic disorder, is characterized by the accumulation of copper in the liver and brain, resulting in a range of clinical symptoms. The clinical manifestations of...
10.
Qiu X, Zhang H, Tang Z, Fan Y, Yuan W, Feng C, et al.
Chin Med J (Engl) . 2023 Nov; 137(12):1453-1464. PMID: 37962205
Background: Homoharringtonine (HHT) is an effective anti-inflammatory, anti-viral, and anti-tumor protein synthesis inhibitor that has been applied clinically. Here, we explored the therapeutic effects of HHT in a mouse heart...