Heather R Lucas
Overview
Explore the profile of Heather R Lucas including associated specialties, affiliations and a list of published articles.
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Articles
30
Citations
337
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Recent Articles
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Lucas H, Kim E, Ghiladi R
J Inorg Biochem
. 2023 Feb;
241:112142.
PMID: 36804183
No abstract available.
4.
Lucas H, Kim E, Ghiladi R
J Inorg Biochem
. 2023 Feb;
241:112143.
PMID: 36740483
No abstract available.
5.
Curry A, Fernandez R, Pagani T, Abeyawardhane D, Trahan M, Lucas H
Life (Basel)
. 2020 Jul;
10(8).
PMID: 32726960
Parkinson's disease (PD) is the second most common neurological disease and belongs to a group of neurodegenerative disorders called synucleinopathies in which pathological aggregates of N-terminally acetylated α-synuclein (α-Syn) accumulate...
6.
Murgas C, Green S, Forney A, Korba R, An S, Kitten T, et al.
ACS Infect Dis
. 2020 Apr;
6(7):1906-1921.
PMID: 32329608
is an oral commensal bacterium, but it can colonize pre-existing heart valve vegetations if introduced into the bloodstream, leading to infective endocarditis. Loss of Mn- or Fe-cofactored virulence determinants are...
7.
Abeyawardhane D, Curry A, Forney A, Roberts J, Lucas H
J Biol Inorg Chem
. 2019 Nov;
24(8):1261-1268.
PMID: 31728738
Metal dyshomeostasis has long been linked to Parkinson's disease (PD), and the amyloidogenic protein α-synuclein (αS) is universally recognized as a key player in PD pathology. Structural consequences upon coordination...
8.
Abeyawardhane D, Lucas H
Oxid Med Cell Longev
. 2019 Nov;
2019:4609702.
PMID: 31687080
The etiology of Parkinson's disease (PD) is linked with cellular inclusions in the region of the brain that are enriched in the misfolded presynaptic protein -synuclein (S) and death of...
9.
Lucas H, Fernandez R
Neural Regen Res
. 2019 Oct;
15(3):407-415.
PMID: 31571649
N-acetylated α-synuclein (αSyn) has long been established as an intrinsically disordered protein associated with a dysfunctional role in Parkinson's disease. In recent years, a physiologically relevant, higher order conformation has...
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Abeyawardhane D, Fernandez R, Heitger D, Crozier M, Wolver J, Lucas H
J Am Chem Soc
. 2018 Nov;
140(49):17086-17094.
PMID: 30422655
Aggregation of the neuronal protein α-synuclein (αS) is a critical factor in the pathogenesis of Parkinson's disease. Analytical methods to detect post-translational modifications of αS are under development, yet the...