Heather Leu
Overview
Explore the profile of Heather Leu including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
257
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0
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Recent Articles
1.
Jiang Q, Isquith J, Zipeto M, Diep R, Pham J, Delos Santos N, et al.
Cancer Cell
. 2019 Jan;
35(1):81-94.e7.
PMID: 30612940
Adenosine deaminase associated with RNA1 (ADAR1) deregulation contributes to therapeutic resistance in many malignancies. Here we show that ADAR1-induced hyper-editing in normal human hematopoietic progenitors impairs miR-26a maturation, which represses...
2.
Lazzari E, Mondala P, Santos N, Miller A, Pineda G, Jiang Q, et al.
Nat Commun
. 2017 Dec;
8(1):1922.
PMID: 29203771
Despite novel therapies, relapse of multiple myeloma (MM) is virtually inevitable. Amplification of chromosome 1q, which harbors the inflammation-responsive RNA editase adenosine deaminase acting on RNA (ADAR)1 gene, occurs in...
3.
Goff D, Court Recart A, Sadarangani A, Chun H, Barrett C, Krajewska M, et al.
Cell Stem Cell
. 2013 Jan;
12(3):316-28.
PMID: 23333150
Leukemia stem cells (LSCs) play a pivotal role in the resistance of chronic myeloid leukemia (CML) to tyrosine kinase inhibitors (TKIs) and its progression to blast crisis (BC), in part,...
4.
Raheem O, Kulidjian A, Wu C, Jeong Y, Yamaguchi T, Smith K, et al.
J Transl Med
. 2011 Nov;
9:185.
PMID: 22035283
Unlabelled: Prostate cancer metastasizes to bone in the majority of patients with advanced disease leading to painfully debilitating fractures, spinal compression and rapid decline. In addition, prostate cancer bone metastases...