He-Yao Wang
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Explore the profile of He-Yao Wang including associated specialties, affiliations and a list of published articles.
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64
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943
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Recent Articles
1.
Pu D, Wang T, Zhang X, Gao J, Zhang R, Li X, et al.
RSC Adv
. 2022 May;
8(12):6425-6435.
PMID: 35540406
Investigation of the leaves and stems of resulted in the isolation of twelve new abietane diterpenoids, szemaoenoids A-L (1-12), together with four known abietane diterpenoids (13-16). The structures involved two...
2.
He Y, Chen M, Wang T, Zhang M, Li Y, Wang H, et al.
Eur J Med Chem
. 2021 Jul;
224:113720.
PMID: 34332399
Fatty acid-binding protein 4 (FABP4) and fatty acid-binding protein 5 (FABP5) are promising therapeutic targets for the treatment of various metabolic diseases. However, the weak potency, low selectivity over FABP3,...
3.
Fan M, Wang T, Peng L, Huang J, Wu X, Wang H, et al.
Chem Biodivers
. 2021 Jul;
18(9):e2100517.
PMID: 34292661
A new neo-clerodane diterpenoid, salvihispin H (1), and six known ones (2-7) were identified from the aerial parts of Salvia hispanica L. The structure and absolute configuration of 1 were...
4.
Chen M, Huang J, Gao D, Li Y, Wang H
Basic Clin Pharmacol Toxicol
. 2021 Jun;
129(3):173-182.
PMID: 34128319
Rosiglitazone has been reported to exert dual effects on liver steatosis, and it could exacerbate liver steatosis in obese animal models, which was suggested to be closely related to the...
5.
Yang L, Lei X, Huang Q, Wang T, Sun H, Wang H
Life Sci
. 2021 Jan;
269:119029.
PMID: 33450256
Aims: The present study aimed to disclose a potent and selective GPR120 agonist LXT34 and its anti-diabetic effects. Main Methods: Calcium mobilization assay was used to measure the agonistic potency...
6.
A novel low systemic diacylglycerol acyltransferase 1 inhibitor, Yhhu2407, improves lipid metabolism
Huang J, Guo B, Lin F, Zeng L, Wang T, Dang X, et al.
Eur J Pharm Sci
. 2020 Dec;
158:105683.
PMID: 33347980
Diacylglycerol acyltransferase 1 (DGAT1) plays a pivotal role in lipid metabolism by catalyzing the committed step in triglyceride (TG) synthesis and has been considered as a potential therapeutic target of...
7.
Wang X, Zhu B, Jia Q, Li Y, Wang T, Wang H
J Agric Food Chem
. 2020 Oct;
68(45):12617-12630.
PMID: 33125846
In our previous study, cinnamtannin D1 (CD-1), one of the A-type procyanidin oligomers isolated from , was reported to have the activity of antiapoptosis in palmitic acid-treated pancreatic β cells...
8.
Huang J, Guo B, Wang G, Zeng L, Hu Y, Wang T, et al.
Acta Pharmacol Sin
. 2020 Aug;
42(2):264-271.
PMID: 32737468
Previous studies demonstrated that prolonged exposure to elevated levels of free fatty acids (FFA), especially saturated fatty acids, could lead to pancreatic β-cell apoptosis, which plays an important role in...
9.
Dou H, Wang T, Su H, Gao D, Xu Y, Li Y, et al.
Endocrine
. 2019 Dec;
67(3):587-596.
PMID: 31845180
Purpose: Fatty acid binding protein 4 (FABP4) has been demonstrated to be secreted from adipocytes in an unconventional pathway associated with lipolysis. Circulating FABP4 is elevated in metabolic disorders and...
10.
Sun P, Li K, Wang T, Ji J, Wang Y, Chen K, et al.
J Agric Food Chem
. 2019 Jul;
67(32):8839-8846.
PMID: 31334651
Natural products are one of the main sources for discovering new lead compounds. We previously reported that cinnamon extract has a promising effect in regulating lipid tissue volume and insulin...