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Haruko Hayasaka

Explore the profile of Haruko Hayasaka including associated specialties, affiliations and a list of published articles. Areas
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Articles 34
Citations 644
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Recent Articles
1.
Tanaka K, Hayasaka H, Matsusaka T
PLoS One . 2024 May; 19(5):e0303910. PMID: 38805434
Dach1 is highly expressed in normal podocytes, but this expression rapidly disappears after podocyte injury. To investigate the role of Dach1 in podocytes in vivo, we analyzed global, podocyte-specific, and...
2.
Yamamoto M, Takai M, Yashiro N, Hayasaka H, Tsujiuchi T
Biochem Biophys Res Commun . 2024 Apr; 715:149982. PMID: 38676998
The tumor microenvironment is an extremely complex composed of cancer cells and various non-cancer cells, including lymphatic endothelial cells. Lysophosphatidic acid (LPA) receptors (LPA to LPA) activate a variety of...
3.
Fujie R, Kurowarabe K, Yamada Y, Fujiwara K, Nakatani H, Tsutsumi K, et al.
Heliyon . 2023 Sep; 9(8):e19215. PMID: 37664721
The chemokine CCL21 regulates immune and cancer cell migration through its receptor CCR7. The gene encodes the isoform CCL21-Ser, predominantly expressed in the thymic medulla and the secondary lymphoid tissues....
4.
Miyamoto M, Kawato Y, Fujie R, Kurowarabe K, Fujiwara K, Nobusawa R, et al.
Cancer Sci . 2023 Jul; 114(9):3509-3522. PMID: 37421165
CCL21-Ser, a chemokine encoded by the Ccl21a gene, is constitutively expressed in the thymic epithelial cells and stromal cells of secondary lymphoid organs. It regulates immune cell migration and survival...
5.
Sato M, Matsuo K, Susami Y, Yamashita A, Hayasaka H, Hara Y, et al.
Int Immunol . 2023 Jun; 35(9):437-446. PMID: 37279584
CCR4 is a major trafficking receptor for T-helper (Th) 2 cells and Th17 cells and is considered as a potential therapeutic target for atopic dermatitis (AD). The CCR4 ligands CCL17...
6.
Tsujioka M, Miyazawa K, Ohmuraya M, Nibe Y, Shirokawa T, Hayasaka H, et al.
Cell Death Dis . 2023 Apr; 14(4):256. PMID: 37031228
Numerous studies have investigated the various cellular responses against genotoxic stress, including those mediated by focal adhesions. We here identified a novel type of focal adhesion remodelling that occurs under...
7.
Hayashi R, Nakatani H, Kawahata H, Fujie R, Kurowarabe K, Hayasaka H
Bioanalysis . 2023 Jan; 14(22):1413-1421. PMID: 36655683
Although cell-mediated cytotoxicity has been evaluated with various protocols, methods for monitoring cytotoxicity in a time series have not been established. This work describes a method for evaluating cytotoxicity using...
8.
Shintani A, Fukai S, Nobusawa R, Taniguchi K, Hatatani T, Nagai H, et al.
Curr Res Immunol . 2022 Sep; 3:175-185. PMID: 36045707
Lymphocytes regulate the immune response by circulating between the vascular and lymphatic systems. High endothelial venules, HEVs, special blood vessels expressing selective adhesion molecules, such as PNAd and MAdCAM-1, mediate...
9.
Hayasaka H, Yoshida J, Kuroda Y, Nishiguchi A, Matsusaki M, Kishimoto K, et al.
Cancer Sci . 2022 Feb; 113(4):1338-1351. PMID: 35133060
Chemokines are a family of cytokines that mediate leukocyte trafficking and are involved in tumor cell migration, growth, and progression. Although there is emerging evidence that multiple chemokines are expressed...
10.
Kobayashi D, Sugiura Y, Umemoto E, Takeda A, Ueta H, Hayasaka H, et al.
Front Immunol . 2022 Jan; 12:786595. PMID: 35003105
Whereas adenosine 5'-triphosphate (ATP) is the major energy source in cells, extracellular ATP (eATP) released from activated/damaged cells is widely thought to represent a potent damage-associated molecular pattern that promotes...