Harini Krishnan
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Explore the profile of Harini Krishnan including associated specialties, affiliations and a list of published articles.
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31
Citations
528
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Recent Articles
1.
Nath V, Krishnan H, Mishra S, Raghu P
J Cell Biol
. 2025 Mar;
224(5).
PMID: 40042442
Membrane contact sites (MCS) between the plasma membrane (PM) and endoplasmic reticulum (ER) regulate Ca2+ influx. However, the mechanisms by which cells modulate ER-PM MCS density are not understood, and...
2.
Krishnan H, Ahmed S, Hubbard S, Miller W
FEBS J
. 2024 Oct;
291(24):5435-5454.
PMID: 39428852
DAF-2, the Caenorhabditis elegans insulin-like receptor homolog, regulates larval development, metabolism, stress response, and lifespan. The availability of numerous daf-2 mutant alleles has made it possible to elucidate the genetic...
3.
Stark L, Fenker K, Krishnan H, Malone M, Peterson R, Cowan R, et al.
J Am Med Inform Assoc
. 2024 Jul;
31(12):2837-2848.
PMID: 38981117
Objectives: We describe new curriculum materials for engaging secondary school students in exploring the "big data" in the NIH All of Us Research Program's Public Data Browser and the co-design...
4.
Mishra S, Manohar V, Chandel S, Manoj T, Bhattacharya S, Hegde N, et al.
Life Sci Alliance
. 2024 Mar;
7(6).
PMID: 38499328
Lipid transfer proteins mediate the transfer of lipids between organelle membranes, and the loss of function of these proteins has been linked to neurodegeneration. However, the mechanism by which loss...
5.
Raghu P, Sharma Y, Suseela Devi A, Krishnan H
J Biosci
. 2024 Feb;
49.
PMID: 38383971
Diseases of the human nervous system are an important cause of morbidity and mortality worldwide. These disorders arise out of multiple aetiologies of which rare genetic mutations in genes vital...
6.
Krishnan H, Ahmed S, Hubbard S, Miller W
FASEB J
. 2023 Dec;
38(1):e23355.
PMID: 38071609
Drosophila melanogaster (fruit fly) insulin receptor (D-IR) is highly homologous to the human counterpart. Like the human pathway, D-IR responds to numerous insulin-like peptides to activate cellular signals that regulate...
7.
Saha S, Krishnan H, Raghu P
Life Sci Alliance
. 2023 Dec;
7(2).
PMID: 38056909
Lithium (Li) is widely used as a mood stabilizer to treat bipolar affective disorder. However, the molecular targets of Li that underpin its therapeutic effect remain unresolved. Inositol monophosphatase (IMPA1)...
8.
Ghosh A, Venugopal A, Shinde D, Sharma S, Krishnan M, Mathre S, et al.
Life Sci Alliance
. 2023 Jun;
6(9).
PMID: 37316298
Phosphatidylinositol 3-phosphate (PI3P) and phosphatidylinositol 5-phosphate (PI5P) are low-abundance phosphoinositides crucial for key cellular events such as endosomal trafficking and autophagy. Phosphatidylinositol 5-phosphate 4-kinase (PIP4K) is an enzyme that regulates...
9.
Krishnan H, Basak B, Nath V, Mishra S, Raghu P
J Biomol Struct Dyn
. 2023 Feb;
41(22):13368-13382.
PMID: 36803287
Lipid transfer proteins (LTPs) that shuttle lipids at membrane contact sites (MCS) play an important role in maintaining cellular homeostasis. One such important LTP is the Retinal Degeneration B (RDGB)...
10.
Retzbach E, Sheehan S, Krishnan H, Zheng H, Zhao C, Goldberg G
Mol Carcinog
. 2022 Apr;
61(7):677-689.
PMID: 35472679
The Src tyrosine kinase is a strong tumor promotor. Over a century of research has elucidated fundamental mechanisms that drive its oncogenic potential. Src phosphorylates effector proteins to promote hallmarks...