Harini Chakravarthy
Overview
Explore the profile of Harini Chakravarthy including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
369
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0
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Recent Articles
1.
Hsueh B, Burns V, Pauerstein P, Holzem K, Ye L, Engberg K, et al.
Sci Rep
. 2017 Jul;
7(1):5899.
PMID: 28724969
Three-dimensional tissue-structural relationships are not well captured by typical thin-section histology, posing challenges for the study of tissue physiology and pathology. Moreover, while recent progress has been made with intact...
2.
Chakravarthy H, Gu X, Enge M, Dai X, Wang Y, Damond N, et al.
Cell Metab
. 2017 Feb;
25(3):622-634.
PMID: 28215845
Insulin-producing pancreatic β cells in mice can slowly regenerate from glucagon-producing α cells in settings like β cell loss, but the basis of this conversion is unknown. Moreover, it remains...
3.
Banerjee R, Cyphert H, Walker E, Chakravarthy H, Peiris H, Gu X, et al.
Diabetes
. 2016 May;
65(8):2331-41.
PMID: 27217483
β-Cell proliferation and expansion during pregnancy are crucial for maintaining euglycemia in response to increased metabolic demands placed on the mother. Prolactin and placental lactogen signal through the prolactin receptor...
4.
Yusuf D, Butland S, Swanson M, Bolotin E, Ticoll A, Cheung W, et al.
Genome Biol
. 2012 Mar;
13(3):R24.
PMID: 22458515
Here we present the Transcription Factor Encyclopedia (TFe), a new web-based compendium of mini review articles on transcription factors (TFs) that is founded on the principles of open access and...
5.
Chakravarthy H, Ormsbee B, Mallanna S, Rizzino A
FASEB J
. 2010 Sep;
25(1):206-18.
PMID: 20876214
The rapid formation of numerous tissues during development is highly dependent on the swift activation of key developmental regulators. Recent studies indicate that many key regulatory genes are repressed in...
6.
Wilder P, Chakravarthy H, Hollingsworth M, Rizzino A
Biochem Biophys Res Commun
. 2009 Mar;
381(4):706-11.
PMID: 19254697
There is a pressing need for new therapies to treat pancreatic cancer. In principle, this could be achieved by taking advantage of signaling pathways that are active in tumor, but...
7.
Chakravarthy H, Boer B, Desler M, Mallanna S, McKeithan T, Rizzino A
J Cell Physiol
. 2008 Mar;
216(3):651-62.
PMID: 18366076
Sox2 and Oct-3/4 function as master regulators during mammalian embryogenesis, where they are believed to regulate a critical gene regulatory network by cooperatively binding to DNA regulatory regions composed of...
8.
Boer B, Kopp J, Mallanna S, Desler M, Chakravarthy H, Wilder P, et al.
Nucleic Acids Res
. 2007 Feb;
35(6):1773-86.
PMID: 17324942
Recent studies have identified large sets of genes in embryonic stem and embryonal carcinoma cells that are associated with the transcription factors Sox2 and Oct-3/4. Other studies have shown that...