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Harin A Karunajeewa

Explore the profile of Harin A Karunajeewa including associated specialties, affiliations and a list of published articles. Areas
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Citations 638
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Recent Articles
1.
Lloyd M, Tang C, Callander E, Janus E, Karahalios A, Skinner E, et al.
Pilot Feasibility Stud . 2019 Aug; 5:97. PMID: 31372236
Background: Community-acquired pneumonia (CAP) is a leading cause of morbidity and mortality worldwide, but few studies have evaluated the feasibility of routine patient-reported outcome measures (PROMs) in this illness. This...
2.
Desmond L, Lloyd M, Ryan S, Janus E, Karunajeewa H
Commun Dis Intell (2018) . 2019 Apr; 43. PMID: 30982246
Background: Community-Acquired Pneumonia (CAP) is one of the highest health burden conditions in Australia. Disease notifications and other data from routine diagnosis suffers from selection bias that may misrepresent the...
3.
Salman S, Baiwog F, Page-Sharp M, Kose K, Karunajeewa H, Mueller I, et al.
Int J Antimicrob Agents . 2017 Jul; 50(4):542-551. PMID: 28669839
Despite extensive use and accumulated evidence of safety, there have been few pharmacokinetic studies from which appropriate chloroquine (CQ) dosing regimens could be developed specifically for pregnant women. Such optimised...
4.
Salman S, Baiwog F, Page-Sharp M, Griffin S, Karunajeewa H, Mueller I, et al.
Antimicrob Agents Chemother . 2017 Mar; 61(5). PMID: 28242669
Optimal dosing of sulfadoxine-pyrimethamine (SP) as intermittent preventive treatment in pregnancy remains to be established, particularly when coadministered with azithromycin (AZI). To further characterize SP pharmacokinetics in pregnancy, plasma concentration-time...
5.
Karunajeewa H, Mueller I
BMC Med . 2016 Jun; 14:93. PMID: 27317420
There has been increasing interest in the role of malaria drugs in preventing malaria transmission from humans to mosquitoes, which would help augment malaria control and elimination strategies. Nevertheless, only...
6.
Karunajeewa H
BMC Med . 2015 Oct; 13:251. PMID: 26429335
The discovery and development of the artemisinin class of antimalarial drugs is one of the great recent success stories of global health. However, after at least two decades of successful...
7.
Manning L, Laman M, Page-Sharp M, Salman S, Hwaiwhanje I, Morep N, et al.
Antimicrob Agents Chemother . 2011 Aug; 55(11):5027-33. PMID: 21859936
Although the artemisinin-associated neurotoxicity identified in vitro and in animal studies has not been confirmed clinically, only one adult study has measured cerebrospinal fluid (CSF) concentrations after administration of conventional...
8.
Barnadas C, Koepfli C, Karunajeewa H, Siba P, Davis T, Mueller I
Antimicrob Agents Chemother . 2011 Jun; 55(9):4479-81. PMID: 21709097
Plasmodium vivax intervention trials customarily report uncorrected treatment failure rates. Application of recrudescence-reinfection genotyping and drug resistance single-nucleotide polymorphism typing to a 4-arm comparative efficacy trial illustrated that molecular approaches...
9.
von Ahsen N, Tzvetkov M, Karunajeewa H, Gomorrai S, Ura A, Brockmoller J, et al.
Int J Mol Epidemiol Genet . 2011 May; 1(4):310-9. PMID: 21532842
Purpose: A high frequency of previously unknown CYP2D6 alleles have been reported in Oceania populations. Genetic and functional properties of these alleles remain unknown. Methods: We performed analyses of the...
10.
Davis W, Clarke P, Siba P, Karunajeewa H, Davy C, Mueller I, et al.
Bull World Health Organ . 2011 Mar; 89(3):211-20. PMID: 21379417
Objective: To compare the cost-effectiveness of conventional antimalarial therapy with that of three artemisinin combination treatment regimens in children from Papua New Guinea aged 6 to 60 months. Methods: An...