Harikrishnan Radhakrishnan
Overview
Explore the profile of Harikrishnan Radhakrishnan including associated specialties, affiliations and a list of published articles.
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12
Citations
111
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Recent Articles
1.
Radhakrishnan H, Newmyer S, Javitz H, Bhatnagar P
Proc Natl Acad Sci U S A
. 2024 Sep;
121(40):e2318687121.
PMID: 39312667
The CD4 T cell, when engineered with a chimeric antigen receptor (CAR) containing specific intracellular domains, has been transformed into a zero-order drug-delivery platform. This introduces the capability of prolonged,...
2.
Naidu S, Karnati S, Radhakrishnan H, Gupta A
Front Genet
. 2024 Aug;
15:1450309.
PMID: 39119580
No abstract available.
3.
Radhakrishnan H, Newmyer S, Ssemadaali M, Javitz H, Bhatnagar P
Bioeng Transl Med
. 2024 Jan;
9(1):e10605.
PMID: 38193126
Primary T cell has been transformed into a that synthesizes complex biologics at the disease site with spatiotemporal resolution. This broadly applicable technology can circumvent toxicities due to systemic administration...
4.
Ssemadaali M, Arredondo J, Buser E, Newmyer S, Radhakrishnan H, Javitz H, et al.
Bioeng Transl Med
. 2023 May;
8(3):e10508.
PMID: 37206248
We have developed a serology test platform for identifying individuals with prior exposure to specific viral infections and provide data to help reduce public health risks. The serology test composed...
5.
Newmyer S, Ssemadaali M, Radhakrishnan H, Javitz H, Bhatnagar P
Bioeng Transl Med
. 2023 Mar;
8(2):e10434.
PMID: 36925710
This work reports on an engineered cell that-when electrically stimulated-synthesizes a desired protein, that is, . The platform has been used to express interferon (IFN)-β as a universal antiviral protein....
6.
Kortum B, Radhakrishnan H, Zincke F, Sachse C, Burock S, Keilholz U, et al.
Oncogene
. 2022 Aug;
41(39):4446-4458.
PMID: 36008464
Colorectal cancer (CRC) is the second-most common malignant disease worldwide, and metastasis is the main culprit of CRC-related death. Metachronous metastases remain to be an unpredictable, unpreventable, and fatal complication,...
7.
Ssemadaali M, Newmyer S, Radhakrishnan H, Arredondo J, Javitz H, Dandekar S, et al.
Microbiol Spectr
. 2022 Jul;
10(4):e0073122.
PMID: 35852348
We have engineered a cell that can be used for diagnosing active severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections. Isolation of individuals with active infections offers an effective solution...
8.
Repellin C, Ssemadaali M, Newmyer S, Radhakrishnan H, Javitz H, Bhatnagar P
Adv Biol (Weinh)
. 2021 Apr;
5(7):e2000298.
PMID: 33871182
The NK-92MI, a fast-growing cytolytic cell line with a track record of exerting clinical efficacy, is transformed into a vector for synthesizing calibrated amounts of desired engineered proteins at our...
9.
Radhakrishnan H, Javitz H, Bhatnagar P
Adv Biosyst
. 2020 May;
4(6):e1900288.
PMID: 32390316
A process for maximizing the titer of lentivirus particles, deemed to be a necessity for transducing primary cells, is developed. Lentivirus particles, with a set of transgenes encoding an artificial...
10.
Radhakrishnan H, Walther W, Zincke F, Kobelt D, Imbastari F, Erdem M, et al.
Cancer Metastasis Rev
. 2019 Jan;
37(4):805-820.
PMID: 30607625
Deciphering the paths to metastasis and identifying key molecules driving this process is one important issue for understanding and treatment of cancer. Such a key driver molecule is Metastasis Associated...