Harendra S Parekh
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Explore the profile of Harendra S Parekh including associated specialties, affiliations and a list of published articles.
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56
Citations
567
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Recent Articles
1.
Shreya A, Pandey A, Kulkarni S, Bhaskar K, Parekh H, Mutalik S
Sci Rep
. 2024 Nov;
14(1):28225.
PMID: 39548220
Asenapine maleate (ASPM) is a second-generation atypical antipsychotic that is approved for treating acute schizophrenia and bipolar disorder in adults by the US FDA. The major downside of ASPM therapy...
2.
Almahmoud A, Parekh H, Paterson B, Tupally K, Vegh V
Theranostics
. 2024 Sep;
14(13):5022-5101.
PMID: 39267777
The potential of intranasal administered imaging agents to altogether bypass the blood-brain barrier offers a promising non-invasive approach for delivery directly to the brain. This review provides a comprehensive analysis...
3.
Thapa R, Pandey P, Parat M, Gurung S, Parekh H
Int J Pharm
. 2024 Mar;
655:124054.
PMID: 38548071
Direct, reliable, controlled, and sustained drug delivery to female reproductive tract (FRT) remains elusive, with conventional dosage forms falling way short of the mark, leading to premature leakage, erratic drug...
4.
Harrop A, Tupally K, Pandey P, Parekh H
Mol Pharm
. 2023 Nov;
20(12):5954-5980.
PMID: 37962352
Bioactive glasses (BGs) are widely used in orthopedic and dental applications for their ability to stimulate endogenous bone formation and regeneration. BG applications more recently broadened to include soft tissue...
5.
Mutalik S, Gaikwad S, Fernandes G, More A, Kulkarni S, Fayaz S, et al.
Life Sci
. 2023 Nov;
334:122226.
PMID: 37918627
Aims: Development and characterization of LAM and DTG loaded liposomes conjugated anti-CD4 antibody and peptide dendrimer (PD2) to improve the therapeutic efficacy and to achieve targeted treatment for HIV infection....
6.
Bakshi S, Pandey P, Mohammed Y, Wang J, Sailor M, Popat A, et al.
J Control Release
. 2023 Sep;
363:452-463.
PMID: 37769816
Intranasal delivery is the most preferred route of drug administration for treatment of a range of nasal conditions including chronic rhinosinusitis (CRS), caused by an infection and inflammation of the...
7.
Rad I, Chapman L, Tupally K, Veidt M, Al-Sadiq H, Sullivan R, et al.
Theranostics
. 2023 Jul;
13(11):3582-3638.
PMID: 37441595
Ultrasound has long been identified as a promising, non-invasive modality for improving ocular drug delivery across a range of indications. Yet, with 20 years of learnings behind us, clinical translation...
8.
Lohman R, Tupally K, Kandale A, Cabot P, Parekh H
Front Pharmacol
. 2023 Mar;
14:1150313.
PMID: 36937883
Kappa opioid receptors have exceptional potential as an analgesic target, seemingly devoid of many problematic Mu receptor side-effects. Kappa-selective, small molecule pharmaceutical agents have been developed, but centrally mediated side-effects...
9.
Tan M, Pandey P, Lohman R, Falconer J, Siskind D, Parekh H
Mol Pharm
. 2022 Sep;
19(11):4055-4066.
PMID: 36149013
Clozapine is the most effective antipsychotic for treatment-resistant schizophrenia. However, it causes many adverse drug reactions (ADRs), which lead to poor treatment outcomes. Nose-to-brain (N2B) drug delivery offers a promising...
10.
Jing J, Tupally K, Kokil G, Qu Z, Chen S, Parekh H
RSC Adv
. 2022 May;
9(5):2458-2463.
PMID: 35520530
The discovery that a cane toad poison-derived steroid, bufalin can significantly impact cancer cell proliferation supports its potential use in cancer therapy. However, its poor aqueous solubility and tissue deposition...