Hao-Zheng Li
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Explore the profile of Hao-Zheng Li including associated specialties, affiliations and a list of published articles.
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15
Citations
54
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Recent Articles
1.
Wang X, Zhang C, Zhang T, Li H, Liu Y, Xu Z, et al.
FEBS J
. 2024 Mar;
291(13):2918-2936.
PMID: 38525648
In recent years, a few asparaginyl endopeptidases (AEPs) from certain higher plants have been identified as efficient peptide ligases with wide applications in protein labeling and cyclic peptide synthesis. Recently,...
2.
Li H, Wang Y, Hu W, Liu Y, Xu Z, Guo Z
Amino Acids
. 2023 Sep;
55(11):1557-1562.
PMID: 37689599
Our recent study confirmed that the mature neuropeptide FAM237A, also known as neurosecretory protein GL (NPGL), is an efficient agonist for GPR83. The paralog FAM237B was previously reported as a...
3.
Li H, Wang Y, Zheng Y, Liu Y, Xu Z, Guo Z
Biochem Biophys Res Commun
. 2023 Sep;
679:110-115.
PMID: 37677979
The peptide hormone ghrelin (an agonist) and LEAP2 (an antagonist) play important functions in energy metabolism via their receptor GHSR, an A-class G protein-coupled receptor. Ghrelin, LEAP2, and GHSR are...
4.
Li H, Wang Y, Shao X, Liu Y, Xu Z, Wang S, et al.
FEBS J
. 2023 Feb;
290(13):3461-3479.
PMID: 36853120
G protein-coupled receptor 83 (GPR83) is primarily expressed in the brain and is implicated in the regulation of energy metabolism and some anxiety-related behaviours. Recently, the PCSK1N/proSAAS-derived peptide PEN, the...
5.
Li H, Shao X, Wang Y, Liu Y, Xu Z, Guo Z
Biochimie
. 2023 Jan;
209:10-19.
PMID: 36669723
Recently, liver-expressed antimicrobial peptide 2 (LEAP2) was identified as an endogenous antagonist and an inverse agonist of the ghrelin receptor GHSR. However, its functions in lower vertebrates are not well...
6.
Li H, Shao X, Shou L, Li N, Liu Y, Xu Z, et al.
ACS Med Chem Lett
. 2022 Oct;
13(10):1655-1662.
PMID: 36262400
The orexigenic peptide ghrelin exerts important functions in energy metabolism and has therapeutic potential to treat certain diseases. Native ghrelin carries an essential -fatty acyl moiety; however, this post-translational modification...
7.
Sun X, Li H, Xie D, Gao S, Huang X, Guan H, et al.
J Transl Med
. 2022 Oct;
20(1):456.
PMID: 36199069
Background: Epithelial-to-mesenchymal transition (EMT) is a critical event contributing to more aggressive phenotypes in cancer cells. EMT is frequently activated in radiation-targeted cells during the course of radiotherapy, which often...
8.
Zhu W, Cai E, Li H, Wang P, Shen A, Popp J, et al.
Angew Chem Int Ed Engl
. 2021 Jul;
60(40):21846-21852.
PMID: 34227191
Stimulated Raman scattering (SRS) microscopy in combination with innovative tagging strategies offers great potential as a universal high-throughput biomedical imaging tool. Here, we report rationally tailored small molecular monomers containing...
9.
Li H, Shou L, Shao X, Li N, Liu Y, Xu Z, et al.
Amino Acids
. 2021 May;
53(6):939-949.
PMID: 33966114
Recent studies have demonstrated that liver-expressed antimicrobial peptide 2 (LEAP2) antagonizes the ghrelin receptor GHSR1a in mammals. However, its antagonistic function in lower vertebrates has not yet been tested. LEAP2...
10.
Li H, Shao X, Shou L, Li N, Liu Y, Xu Z, et al.
Arch Biochem Biophys
. 2021 Apr;
704:108872.
PMID: 33857472
The gastric peptide ghrelin has important functions in energy metabolism and cellular homeostasis by activating growth hormone secretagogue receptor type 1a (GHSR1a). The N-terminal residues of ghrelin orthologs from all...