Hans V Westerhoff
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Explore the profile of Hans V Westerhoff including associated specialties, affiliations and a list of published articles.
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173
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4040
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Recent Articles
1.
Bruggeman F, Remeijer M, Droste M, Salinas L, Wortel M, Planque R, et al.
Biosystems
. 2024 Nov;
:105067.
PMID: 39492480
Since its conception some fifty years ago, metabolic control analysis (MCA) aims to understand how cells control their metabolism by adjusting the activity of their enzymes. Here we extend its...
2.
Martins Dos Santos V, Anton M, Szomolay B, Ostaszewski M, Arts I, Benfeitas R, et al.
F1000Res
. 2024 Jun;
11.
PMID: 36742342
In this white paper, we describe the founding of a new ELIXIR Community - the Systems Biology Community - and its proposed future contributions to both ELIXIR and the broader...
3.
Goglia I, Weglarz-Tomczak E, Gioia C, Liu Y, Virtuoso A, Bonanomi M, et al.
FEBS J
. 2024 Feb;
291(13):2811-2835.
PMID: 38362803
Neuronal differentiation is regulated by nerve growth factor (NGF) and other neurotrophins. We explored the impact of NGF on mitochondrial dynamics and metabolism through time-lapse imaging, metabolomics profiling, and computer...
4.
Hassan Z, Westerhoff H
Toxics
. 2024 Jan;
12(1).
PMID: 38276724
At a great many locations worldwide, the safety of drinking water is not assured due to pollution with arsenic. Arsenic toxicity is a matter of both systems chemistry and systems...
5.
Aerts J, Sarbu S, Brad T, Ehrenfreund P, Westerhoff H
Life (Basel)
. 2023 Nov;
13(11).
PMID: 38004260
Movile Cave, situated in Romania close to the Black Sea, constitutes a distinct and challenging environment for life. Its partially submerged ecosystem depends on chemolithotrophic processes for its energetics, which...
6.
David R, Rybina A, Burel J, Heriche J, Audergon P, Boiten J, et al.
EMBO J
. 2023 Nov;
42(23):e115008.
PMID: 37964598
The main goals and challenges for the life science communities in the Open Science framework are to increase reuse and sustainability of data resources, software tools, and workflows, especially in...
7.
Liu Y, Westerhoff H
NPJ Syst Biol Appl
. 2023 Oct;
9(1):53.
PMID: 37898597
In multicellular organisms cells compete for resources or growth factors. If any one cell type wins, the co-existence of diverse cell types disappears. Existing dynamic Flux Balance Analysis (dFBA) does...
8.
Westerhoff H
Biosystems
. 2023 Aug;
233:104998.
PMID: 37591451
In Microbiology it is often assumed that growth rate is maximal. This may be taken to suggest that the dependence of the growth rate on every enzyme activity is at...
9.
van Niekerk D, Rust E, Bruggeman F, Westerhoff H, Snoep J
Biosystems
. 2023 Aug;
232:104988.
PMID: 37541333
By analysing a large set of models obtained from the JWS Online and Biomodels databases, we tested to what extent the disequilibrium ratio can be used as an estimator for...
10.
Zhang Y, Westerhoff H
Entropy (Basel)
. 2023 Jul;
25(7).
PMID: 37509940
Confronted with thermodynamically adverse output processes, free-energy transducers may shift to lower gears, thereby reducing output per unit input. This option is well known for inanimate machines such as automobiles,...