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Hans H Jensen

Explore the profile of Hans H Jensen including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 5
Citations 178
Followers 0
Related Specialties
Biochemistry
Oncology
Cell Biology
Top 10 Co-Authors
Olaf-Georg Issinger
Brigitte Boldyreff
Thierry Buchou
Karsten Niefind
Claude Cochet
Olivier Blond
Birgitte B Olsen
Lucille Beaudet
Niels Marcussen
Tine L Rasmussen
Published In
Mol Cell Biochem
Mol Cell Biol
Cancer Lett
J Biomol Screen
Affiliations
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Recent Articles
1.
Protein kinase CK2 inhibition is associated with the destabilization of HIF-1α in human cancer cells
Guerra B, Rasmussen T, Schnitzler A, Jensen H, Boldyreff B, Miyata Y, et al.
Cancer Lett . 2014 Dec; 356(2 Pt B):751-61. PMID: 25449433
Screening for protein kinase CK2 inhibitors of the structural diversity compound library (DTP NCI/NIH) led to the discovery of 4-[(E)-(fluoren-9-ylidenehydrazinylidene)-methyl]benzoic acid (E9). E9 induces apoptotic cell death in various cancer...
2.
Expression and purification of PI3 kinase alpha and development of an ATP depletion and an alphascreen PI3 kinase activity assay
Boldyreff B, Rasmussen T, Jensen H, Cloutier A, Beaudet L, Roby P, et al.
J Biomol Screen . 2008 Nov; 13(10):1035-40. PMID: 19036708
Phosphoinositide-3-kinases are important targets for drug development because many proteins in the PI3 kinase signaling pathway are mutated, hyperactivated, or overexpressed in human cancers. Here, the authors coexpressed the human...
3.
Biochemical characterization of the recombinant human Drosophila homologues Timekeeper and Andante involved in the Drosophila circadian oscillator
Rasmussen T, Skjoth I, Jensen H, Niefind K, Boldyreff B, Issinger O
Mol Cell Biochem . 2005 Dec; 274(1-2):151-61. PMID: 16335535
The Drosophila clock proteins timekeeper (CK2a(Tik)) and andante (CK2beta(And)) are mutated CK2alpha and CK2beta subunits, respectively. In order to revisit the hypothesis concerning a perturbation of the beta/beta and/or alpha/beta...
4.
Knocking out the regulatory beta subunit of protein kinase CK2 in mice: gene dosage effects in ES cells and embryos
Blond O, Jensen H, Buchou T, Cochet C, Issinger O, Boldyreff B
Mol Cell Biochem . 2005 Dec; 274(1-2):31-7. PMID: 16335526
Knocking out the regulatory beta subunit of protein kinase CK2 in mice leads to early embryonic lethality. Heterozygous CK2beta (CK2beta+/-) knockout mice do not show an obvious phenotype. However, the...
5.
Disruption of the regulatory beta subunit of protein kinase CK2 in mice leads to a cell-autonomous defect and early embryonic lethality
Buchou T, Vernet M, Blond O, Jensen H, Pointu H, Olsen B, et al.
Mol Cell Biol . 2003 Jan; 23(3):908-15. PMID: 12529396
Protein kinase CK2 is a ubiquitous protein kinase implicated in proliferation and cell survival. Its regulatory beta subunit, CK2beta, which is encoded by a single gene in mammals, has been...