Hans Gerd Nothwang
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Explore the profile of Hans Gerd Nothwang including associated specialties, affiliations and a list of published articles.
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66
Citations
912
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Recent Articles
1.
Lessle S, Ebbers L, Dorflinger Y, Hoppe S, Kaiser M, Nothwang H, et al.
Front Cell Neurosci
. 2024 Dec;
18:1404206.
PMID: 39624646
Activity has long been considered essential for circuit formation and maintenance. This view has recently been challenged by proper synaptogenesis and only mildly affected synapse maintenance in the absence of...
2.
Radulovic T, Rajaram E, Ebbers L, Pagella S, Winklhofer M, Kopp-Scheinpflug C, et al.
Sci Rep
. 2023 Dec;
13(1):21660.
PMID: 38066086
The potassium chloride cotransporter KCC2 is crucial for Cl extrusion from mature neurons and thus key to hyperpolarizing inhibition. Auditory brainstem circuits contain well-understood inhibitory projections and provide a potent...
3.
Bordeynik-Cohen M, Sperber M, Ebbers L, Messika-Gold N, Krohs C, Koffler-Brill T, et al.
RNA Biol
. 2023 Aug;
20(1):629-640.
PMID: 37602850
The peripheral and central auditory subsystems together form a complex sensory network that allows an organism to hear. The genetic programs of the two subsystems must therefore be tightly coordinated...
4.
Saleh A, Ahmed Y, Peters L, Nothwang H
Cell Tissue Res
. 2023 Mar;
392(3):643-658.
PMID: 36961563
The mammalian and avian auditory brainstem likely arose by independent evolution. To compare the underlying molecular mechanisms, we focused on Atoh7, as its expression pattern in the mammalian hindbrain is...
5.
Hartmann A, Nothwang H
Front Mol Neurosci
. 2022 Aug;
15:964488.
PMID: 35935337
Inhibitory neurotransmission plays a fundamental role in the central nervous system, with about 30-50% of synaptic connections being inhibitory. The action of both inhibitory neurotransmitter, gamma-aminobutyric-acid (GABA) and glycine, mainly...
6.
Krohs C, Korber C, Ebbers L, Altaf F, Hollje G, Hoppe S, et al.
J Neurosci
. 2021 Jul;
41(32):6796-6811.
PMID: 34193555
A point mutation in miR-96 causes non-syndromic progressive peripheral hearing loss and alters structure and physiology of the central auditory system. To gain further insight into the functions of microRNAs...
7.
Saleh A, Nothwang H
J Comp Neurol
. 2021 Jun;
529(15):3477-3496.
PMID: 34180540
The avian auditory hindbrain is a longstanding model for studying neural circuit development. Information on gene regulatory network (GRN) components underlying this process, however, is scarce. Recently, the spatiotemporal expression...
8.
Hartmann A, Fu L, Ziegler C, Winklhofer M, Nothwang H
J Biol Chem
. 2021 May;
296:100793.
PMID: 34019872
K-Cl cotransporters (KCCs) play important roles in physiological processes such as inhibitory neurotransmission and cell-volume regulation. KCCs exhibit significant variations in K affinities, yet recent atomic structures demonstrated that K-...
9.
Schinzel F, Seyfer H, Ebbers L, Nothwang H
J Comp Neurol
. 2021 Mar;
529(11):3032-3045.
PMID: 33786818
The dorsal cochlear nucleus (DCN) is a mammalian-specific nucleus of the auditory system. Anatomically, it is classified as a cerebellum-like structure. These structures are proposed to share genetic programs with...
10.
Krohs C, Bordeynik-Cohen M, Messika-Gold N, Elkon R, Avraham K, Nothwang H
Cell Tissue Res
. 2020 Nov;
383(2):655-666.
PMID: 33156384
The auditory system comprises the auditory periphery, engaged in sound transduction and the central auditory system, implicated in auditory information processing and perception. Recently, evidence mounted that the mammalian peripheral...