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Hans A M Timmermans

Explore the profile of Hans A M Timmermans including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 213
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Recent Articles
1.
Mulder C, Dong Y, Brugghe H, Timmermans H, Tilstra W, Westdijk J, et al.
J Alzheimers Dis . 2016 Apr; 52(3):1111-23. PMID: 27060957
Background: Soluble oligomeric (misfolded) species of amyloid-β (Aβ) are the main mediators of toxicity in Alzheimer's disease (AD). These oligomers subsequently form aggregates of insoluble fibrils that precipitate as extracellular...
2.
Hoogerhout P, Kamphuis W, Brugghe H, Sluijs J, Timmermans H, Westdijk J, et al.
PLoS One . 2011 Apr; 6(4):e19110. PMID: 21526148
The 39- to 42-residue amyloid β (Aβ) peptide is deposited in extracellular fibrillar plaques in the brain of patients suffering from Alzheimer's Disease (AD). Vaccination with these peptides seems to...
3.
Metz B, Kersten G, Hoogerhout P, Brugghe H, Timmermans H, de Jong A, et al.
J Biol Chem . 2003 Nov; 279(8):6235-43. PMID: 14638685
Formaldehyde is a well known cross-linking agent that can inactivate, stabilize, or immobilize proteins. The purpose of this study was to map the chemical modifications occurring on each natural amino...
4.
van Bleek G, Poelen M, van der Most R, Brugghe H, Timmermans H, Boog C, et al.
J Virol . 2002 Dec; 77(2):980-8. PMID: 12502814
Memory CD4 T-cell responses against respiratory syncytial virus (RSV) were evaluated in peripheral blood mononuclear cells of healthy blood donors with gamma interferon enzyme-linked immunospot (Elispot) assays. RSV-specific responses were...