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Hans-Dieter Volk

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Articles 379
Citations 13748
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Recent Articles
1.
Du W, Noyan F, McCallion O, Drosdek V, Kath J, Glaser V, et al.
Mol Ther . 2025 Feb; 33(3):997-1013. PMID: 39905729
Adoptive transfer of antigen-specific regulatory T cells (Tregs) is a promising strategy to combat immunopathologies in transplantation and autoimmune diseases. However, their low frequency in peripheral blood poses challenges for...
2.
Reis F, Lenz C, Gossen M, Volk H, Drzeniek N
JMIR Med Inform . 2024 Sep; 12:e58478. PMID: 39235317
With the popularization of large language models (LLMs), strategies for their effective and safe usage in health care and research have become increasingly pertinent. Despite the growing interest and eagerness...
3.
Wendering D, Amini L, Schlickeiser S, Farrera-Sal M, Schulenberg S, Peter L, et al.
Sci Adv . 2024 Sep; 10(36):eadn3470. PMID: 39231218
Regulatory T cells (T cells) hold promise for sustainable therapy of immune disorders. Recent advancements in chimeric antigen receptor development and genome editing aim to enhance the specificity and function...
4.
Martini S, Drzeniek N, Stark R, Kollert M, Du W, Reinke S, et al.
Biofabrication . 2024 Jul; 16(4). PMID: 38955197
Plasma cells (PCs) in bone marrow (BM) play an important role in both protective and pathogenic humoral immune responses, e.g. in various malignant and non-malignant diseases such as multiple myeloma,...
5.
Lei H, Li D, Duan M, Zhang Y, Sun Y, She J, et al.
Biochim Biophys Acta Mol Basis Dis . 2024 Apr; 1870(5):167151. PMID: 38565387
Immunoglobulin A vasculitis (IgAV) is the most common vasculitis of childhood. Disordered immune responses play important roles in its pathogenesis, but the comprehensive immune profile of the disease and the...
6.
Kath J, Franke C, Drosdek V, Du W, Glaser V, Fuster-Garcia C, et al.
Blood . 2024 Mar; 143(25):2599-2611. PMID: 38493479
Chimeric antigen receptor (CAR)-redirected immune cells hold significant therapeutic potential for oncology, autoimmune diseases, transplant medicine, and infections. All approved CAR-T therapies rely on personalized manufacturing using undirected viral gene...
7.
Drzeniek N, Kahwaji N, Picht S, Dimitriou I, Schlickeiser S, Moradian H, et al.
Adv Sci (Weinh) . 2024 Mar; 11(21):e2308447. PMID: 38491873
Beyond SARS-CoV2 vaccines, mRNA drugs are being explored to overcome today's greatest healthcare burdens, including cancer and cardiovascular disease. Synthetic mRNA triggers immune responses in transfected cells, which can be...
8.
Sandek A, Gertler C, Valentova M, Jauert N, Wallbach M, Doehner W, et al.
J Clin Med . 2024 Feb; 13(3). PMID: 38337428
: Cardiac cachexia (CC) in chronic heart failure with reduced ejection fraction (HFrEF) is characterized by catabolism and inflammation predicting poor prognosis. Levels of responsible transcription factors like signal transducer...
9.
Schlundt C, Sass R, Bucher C, Bartosch S, Hauser A, Volk H, et al.
Cells . 2024 Jan; 13(1). PMID: 38201244
Background: The healing of a bone injury is a highly complex process involving a multitude of different tissue and cell types, including immune cells, which play a major role in...
10.
Kath J, Franke C, Drosdek V, Du W, Glaser V, Fuster-Garcia C, et al.
bioRxiv . 2023 Dec; PMID: 38116030
Key Points: Integration of ζ-deficient CARs into ζ gene allows generation of functional TCR-ablated CAR-T cells for allogeneic off-the-shelf use ζ-editing platform allows CAR reprogramming of NK cells without affecting...