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Hannu Turpeinen

Explore the profile of Hannu Turpeinen including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 450
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Recent Articles
1.
Zolfaghari Emameh R, Barker H, Turpeinen H, Parkkila S, Hytonen V
Malar J . 2022 Jun; 21(1):189. PMID: 35706028
Background: Malaria is a significant parasitic infection, and human infection is mediated by mosquito (Anopheles) biting and subsequent transmission of protozoa (Plasmodium) to the blood. Carbonic anhydrases (CAs) are known...
2.
Hathaway J, Helio K, Saarinen I, Tallila J, Seppala E, Tuupanen S, et al.
BMC Cardiovasc Disord . 2021 Mar; 21(1):126. PMID: 33673806
Background: Genetic testing in hypertrophic cardiomyopathy (HCM) is a published guideline-based recommendation. The diagnostic yield of genetic testing and corresponding HCM-associated genes have been largely documented by single center studies...
3.
Turpeinen H, Seppala I, Lyytikainen L, Raitoharju E, Hutri-Kahonen N, Levula M, et al.
Hum Genet . 2015 Mar; 134(6):627-36. PMID: 25813623
Proprotein convertase subtilisin/kexin (PCSK) enzymes cleave and convert their immature substrates into biologically active forms. Polymorphisms in the PCSK genes have been reported to associate with human diseases and phenotypes,...
4.
Ojanen M, Turpeinen H, Cordova Z, Hammaren M, Harjula S, Parikka M, et al.
Infect Immun . 2015 Jan; 83(4):1431-42. PMID: 25624351
Tuberculosis is a chronic bacterial disease with a complex pathogenesis. An effective immunity against Mycobacterium tuberculosis requires both the innate and adaptive immune responses, including proper T helper (Th) type...
5.
Impola U, Turpeinen H, Alakulppi N, Linjama T, Volin L, Niittyvuopio R, et al.
Front Immunol . 2014 Sep; 5:405. PMID: 25202311
Successful allogeneic hematopoietic stem cell transplantation (HSCT) depends not only on good HLA match but also on T-cell mediated graft-versus-leukemia (GvL) effect. Natural killer (NK) cells are able to kill...
6.
Turpeinen H, Ortutay Z, Pesu M
Curr Genomics . 2014 Jan; 14(7):453-67. PMID: 24396277
Members of the substilisin/kexin like proprotein convertase (PCSK) protease family cleave and convert immature pro-proteins into their biologically active forms. By cleaving for example prohormones, cytokines and cell membrane proteins,...
7.
Gaafar A, Iqniebi A, Sheereen A, Eldali A, Turpeinen H, Adra C, et al.
Transpl Immunol . 2013 Dec; 30(1):34-9. PMID: 24316141
Objectives: Allograft outcome can be improved with the discovery of risk factors that influence adverse events and may allow individualization of patients' treatment. Rejection is the main hurdle to successful...
8.
Taskinen B, Zmurko J, Ojanen M, Kukkurainen S, Parthiban M, Maatta J, et al.
PLoS One . 2013 Nov; 8(10):e77207. PMID: 24204770
The avidin protein family members are well known for their high affinity towards D-biotin and high structural stability. These properties make avidins valuable tools for a wide range of biotechnology...
9.
Turpeinen H, Oksanen A, Kivinen V, Kukkurainen S, Uusimaki A, Ramet M, et al.
J Biol Chem . 2013 Nov; 288(51):36610-23. PMID: 24178295
Proprotein convertase subtilisin/kexin (PCSK) enzymes convert proproteins into bioactive end products. Although other PCSK enzymes are known to be essential for biological processes ranging from cholesterol metabolism to host defense,...
10.
Spierings E, Kim Y, Hendriks M, Borst E, Sergeant R, Canossi A, et al.
Biol Blood Marrow Transplant . 2013 Jun; 19(8):1244-53. PMID: 23756210
The effect of minor H antigen mismatching on the occurrence of graft-versus-host disease (GvHD) and graft-versus-leukemia (GvL) after HLA-matched hematopoietic stem cell transplantation (HSCT) has mainly been demonstrated in single-center...