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Hanna Rapaport

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Articles 51
Citations 243
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Recent Articles
1.
Arad E, Levi T, Yosefi G, Kass I, Cohen-Erez I, Azoulay Z, et al.
Small . 2024 Aug; 20(47):e2404324. PMID: 39155426
Coassembly of peptide biomaterials offers a compelling avenue to broaden the spectrum of hierarchically ordered supramolecular nanoscale structures that may be relevant for biomedical and biotechnological applications. In this work...
2.
Yosefi G, Kass I, Rapaport H, Bitton R
Biomacromolecules . 2024 Jun; 25(7):4168-4176. PMID: 38902961
We have successfully created self-assembled membranes by combining positively charged (Pro-X-(Phe-X)-Pro) PFX peptides with negatively charged alginate. These PFX/alginate membranes were formed by three different peptides that contain either X...
3.
Ben Ghedalia Peled N, Hoffman D, Barsky L, Zer N, Amar K, Rapaport H, et al.
Biomacromolecules . 2024 Mar; 25(4):2338-2347. PMID: 38499995
Bone is a frequent site for metastatic development in various cancer types, including breast cancer, with a grim prognosis due to the distinct bone environment. Despite considerable advances, our understanding...
4.
Aibinder P, Cohen-Erez I, Rapaport H
Heliyon . 2024 Feb; 10(4):e26095. PMID: 38420433
Here we present the development of nanoparticles (NPs) formulations specifically designed for targeting the antiapoptotic Bcl-2 proteins on the outer membrane of mitochondria with the drug agent ABT-737. The NPs...
5.
Arad E, Pedersen K, Malka O, Mambram Kunnath S, Golan N, Aibinder P, et al.
Nat Commun . 2023 Dec; 14(1):8198. PMID: 38081813
Antibiotic resistance of bacteria is considered one of the most alarming developments in modern medicine. While varied pathways for bacteria acquiring antibiotic resistance have been identified, there still are open...
6.
Yosefi G, Eliraz N, Kolusheva S, Rapaport H, Bitton R
J Colloid Interface Sci . 2023 Sep; 652(Pt B):1897-1907. PMID: 37690297
Self-assembly of macroscopic membranes at the interface between self-assembling peptides and aqueous polymer solutions of opposite charge has been explored mostly due to the membranes' unique hierarchical structure of three...
7.
Ribeiro S, Gnutt D, Azoulay-Ginsburg S, Fetahaj Z, Spurlock E, Lindner F, et al.
Biol Chem . 2023 Aug; 404(10):909-930. PMID: 37555646
Amyotrophic lateral sclerosis (ALS) is a progressive neurological disorder with currently no cure. Central to the cellular dysfunction associated with this fatal proteinopathy is the accumulation of unfolded/misfolded superoxide dismutase...
8.
Dahan S, Aibinder P, Khalfin B, Moran-Gilad J, Rapaport H
ACS Biomater Sci Eng . 2022 Dec; 9(1):352-362. PMID: 36521024
The growing resistance of pathogenic bacteria to conventional antibiotics promotes the development of new antimicrobial agents, including peptides. Hydrogels composed of antimicrobial peptides (AMPs) may be applied as topical treatments...
9.
Arad E, Yosefi G, Kolusheva S, Bitton R, Rapaport H, Jelinek R
ACS Nano . 2022 Jul; 16(8):12889-12899. PMID: 35866668
Glucagon is a prominent peptide hormone, playing central roles in the regulation of glucose blood-level and lipid metabolism. Formation of glucagon amyloid fibrils has been previously reported, although no biological...
10.
Green H, Ochbaum G, Gitelman-Povimonsky A, Bitton R, Rapaport H
RSC Adv . 2022 May; 8(18):10072-10080. PMID: 35540811
The interest in developing functional biomaterials based on designed peptides has been increasing in recent years. The amphiphilic and anionic β-sheet peptide Pro-Asp-(Phe-Asp)-Pro, denoted FD, was previously shown to assemble...