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Hanh Witte

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Articles 41
Citations 881
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Recent Articles
1.
Quiobe S, Kalirad A, Roseler W, Witte H, Wang Y, Rodelsperger C, et al.
Sci Adv . 2025 Mar; 11(11):eadu0875. PMID: 40073139
Environmental influences on traits and associated transgenerational epigenetic inheritance have widespread implications but remain controversial and underlying mechanisms poorly understood. We introduce long-term environmental induction experiments on alternative diets in...
2.
Piskobulu V, Athanasouli M, Witte H, Feldhaus C, Streit A, Sommer R
J Exp Zool B Mol Dev Evol . 2025 Jan; 344(2):94-111. PMID: 39822045
Developmental plasticity, the ability of a genotype to produce different phenotypes in response to environmental conditions, has been subject to intense studies in the last four decades. The self-fertilising nematode...
3.
Almeida A, Rocha H, Raas M, Witte H, Sommer R, Snel B, et al.
J Cell Sci . 2024 Dec; 137(24). PMID: 39698944
Chromosome alignment during mitosis can occur as a consequence of bi-orientation or is assisted by the CENP-E (kinesin-7) motor at kinetochores. We previously found that Indian muntjac chromosomes with larger...
4.
Yoshida K, Witte H, Hatashima R, Sun S, Kikuchi T, Roseler W, et al.
Nat Commun . 2024 Nov; 15(1):9649. PMID: 39511185
The factors contributing to evolution of androdioecy, the coexistence of hermaphrodites and males such as in Caenorhabditis elegans, remains poorly known. However, nematodes exhibit androdioecy in at last 13 genera...
5.
Wighard S, Witte H, Sommer R
Sci Adv . 2024 Apr; 10(15):eadk6062. PMID: 38598624
Experimental genetics in a nematode reveals a key role for developmental plasticity in the evolution of nutritional diversity.
6.
Dardiry M, Eberhard G, Witte H, Rodelsperger C, Lightfoot J, Sommer R
PLoS Biol . 2023 Aug; 21(8):e3002270. PMID: 37590316
The widespread occurrence of phenotypic plasticity across all domains of life demonstrates its evolutionary significance. However, how plasticity itself evolves and how it contributes to evolution is poorly understood. Here,...
7.
Igreja C, Loschko T, Schafer A, Sharma R, Quiobe S, Aloshy E, et al.
Cells . 2022 Dec; 11(23). PMID: 36497133
The detection, manipulation and purification of proteins is key in modern life sciences studies. To achieve this goal, a plethora of epitope tags have been employed in model organisms from...
8.
Lo W, Roca M, Dardiry M, Mackie M, Eberhardt G, Witte H, et al.
Mol Biol Evol . 2022 Dec; 39(12). PMID: 36469861
Transforming growth factor-β (TGF-β) signaling is essential for numerous biologic functions. It is a highly conserved pathway found in all metazoans including the nematode Caenorhabditis elegans, which has also been...
9.
Wighard S, Athanasouli M, Witte H, Rodelsperger C, Sommer R
Genome Biol Evol . 2022 Dec; 14(12). PMID: 36461901
Whole genome duplication (WGD) is often considered a major driver of evolution that leads to phenotypic novelties. However, the importance of WGD for evolution is still controversial because most documented...
10.
Sun S, Witte H, Sommer R
Curr Biol . 2022 Dec; 33(1):15-27.e6. PMID: 36460010
Some nematode predators and parasites form teeth-like denticles that are histologically different from vertebrate teeth, but their biochemical composition remains elusive. Here, we show a role of chitin in the...