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Hang-Lung Chang

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Articles 12
Citations 318
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Recent Articles
1.
Lee W, Tu S, Cheng T, Lin J, Sheu M, Kuo C, et al.
Molecules . 2021 Nov; 26(21). PMID: 34770956
The microenvironment for tumor growth and developing metastasis should be essential. This study demonstrated that the hyaluronic acid synthase 3 (HAS3) protein and its enzymatic product hyaluronic acid (HA) encompassed...
2.
Chang H, Bamodu O, Ong J, Lee W, Yeh C, Tsai J
Cells . 2020 Apr; 9(4). PMID: 32326045
Background: With recorded under-performance of current standard therapeutic strategies as highlighted by high rates of post-treatment (resection or local ablation) recurrence, resistance to chemotherapy, poor overall survival, and an increasing...
3.
Bamodu O, Chang H, Ong J, Lee W, Yeh C, Tsai J
Cells . 2020 Mar; 9(3). PMID: 32197467
Resistance to radiotherapy (IR), with consequent disease recurrence, continues to limit the efficacy of contemporary anticancer treatment for patients with hepatocellular carcinoma (HCC), especially in late stage. Despite accruing evidence...
4.
Ma H, Chang H, Bamodu O, Yadav V, Huang T, Wu A, et al.
Cancers (Basel) . 2019 Jun; 11(6). PMID: 31181620
Increasing evidence shows that hepatocellular carcinoma (HCC) is a principal cause of cancer-related mortality globally, especially among Asian and African populations. Collagen type I α1 (COL1A1) is the major component...
5.
Salah Fararjeh A, Chen L, Ho Y, Cheng T, Liu Y, Chang H, et al.
Cancers (Basel) . 2019 Apr; 11(4). PMID: 31013812
It is well-known that human epidermal growth factor receptor 2 (HER2) is critical for breast cancer (BC) development and progression. Several studies have revealed the role of the ubiquitin/proteasome system...
6.
Lin J, Lee W, Wu H, Wu C, Chen L, Huang C, et al.
Cell Adh Migr . 2019 Feb; 13(1):120-137. PMID: 30744493
The function of small G protein signalling modulators (SGSM1/2/3) in cancer remains unknown. Our findings demonstrated that SGSM2 is a plasma membrane protein that strongly interacted with E-cadherin/β-catenin. SGSM2 downregulation...
7.
Fararjeh A, Tu S, Chen L, Cheng T, Liu Y, Chang H, et al.
Environ Toxicol . 2018 Sep; 34(1):73-82. PMID: 30259641
Breast cancer (BC) is the most common cancer affecting women worldwide and has been associated with active tobacco smoking. Low levels of nicotine (Nic) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), have been detected...
8.
Lee W, Chen L, Lee C, Huang C, Ho Y, Yang P, et al.
Int J Cancer . 2018 Aug; 144(3):615-630. PMID: 30097999
The DNA primase polypeptide 1 (PRIM1) is responsible for synthesizing small RNA primers for Okazaki fragments generated during discontinuous DNA replication. PRIM1 mRNA expression levels in breast tumor samples were...
9.
Lin J, Tu S, Chen L, Huang C, Chang H, Cheng T, et al.
Breast Cancer Res Treat . 2018 Jul; 172(1):45-59. PMID: 30054830
Purpose: Glutathione S-transferase mu 3 (GSTM3) is an enzyme involving in the detoxification of electrophilic compounds by conjugation with glutathione. Higher GSTM3 mRNA levels were reported in patients with ERα-positive...
10.
Fararjeh A, Tu S, Chen L, Liu Y, Lin Y, Chang H, et al.
Hum Pathol . 2018 Jun; 80:219-230. PMID: 29902578
The transcription factor GATA3 plays a significant role in mammary gland development and differentiation. We analyzed expression of GATA3 in breast cancer (BC) cell lines and clinical specimens from BC...