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Hana Kubova

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Articles 83
Citations 591
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Recent Articles
1.
Grigelova A, Mikulecka A, Kubova H
Epilepsy Behav . 2025 Feb; 165:110307. PMID: 40015055
Childhood epilepsy is frequently associated with neurobehavioral comorbidities such as depression, anxiety, cognitive impairments, and social dysfunction, as revealed by both clinical and experimental studies. Despite extensive neurophysiological research, behavioral...
2.
Mares P, Metcalf C, Baloun J, Kubova H
PLoS One . 2025 Jan; 20(1):e0313681. PMID: 39752469
Seizures elicited by corneal 6-Hz stimulation are widely acknowledged as a model of temporal lobe seizures. Despite the intensive research in rodents, no studies hint at this model in developing...
3.
Al-Redouan A, Salaj M, Kubova H, Druga R
Int J Dev Neurosci . 2024 Apr; 84(4):328-341. PMID: 38631684
According to experimental and clinical studies, status epilepticus (SE) causes neurodegenerative morphological changes not only in the hippocampus and other limbic structures, it also affects the thalamus and the neocortex....
4.
Druga R, Mares P, Salaj M, Kubova H
Int J Mol Sci . 2024 Jan; 25(2). PMID: 38279295
The aim of the present study was to analyze the location of degenerating neurons in the dorsal (insular) claustrum (DCL, VCL) and the dorsal, intermediate and ventral endopiriform nucleus (DEn,...
5.
Mares P, Uttl L, Laczo M, BenSalem Z, Vondrakova K, Fabera P, et al.
Pharmaceuticals (Basel) . 2023 Dec; 16(12). PMID: 38139859
: Postictal refractoriness, i.e., the inability to elicit a new epileptic seizure immediately after the first one, is present in mature animals. Immature rats did not exhibit this refractoriness, and...
6.
Kubova H, Mikulecka A, Mares P
Epilepsia Open . 2022 Nov; 8 Suppl 1:S90-S109. PMID: 36352789
Status epilepticus (SE) is the most common neurologic emergency in children. Both clinical and laboratory studies have demonstrated that SE in early life can cause brain damage and permanent behavioral...
7.
Mantegazza M, Auvin S, Barker-Haliski M, Katsarou A, Kubova H, Galanopoulou A, et al.
Epilepsia Open . 2022 Aug; PMID: 35951766
Rodent models of epilepsy remain the cornerstone of research into the mechanisms underlying genetic epilepsy. Reproducibility of experiments using these rodent models, occurring across a diversity of laboratories and commercial...
8.
Katsarou A, Kubova H, Auvin S, Mantegazza M, Barker-Haliski M, Galanopoulou A, et al.
Epilepsia Open . 2022 Aug; PMID: 35950641
Epilepsy syndromes during the early years of life may be attributed to an acquired insult, such as hypoxic-ischemic injury, infection, status epilepticus, or brain trauma. These conditions are frequently modeled...
9.
Fabera P, Uttl L, Kubova H, Tsenov G, Mares P
Int J Mol Sci . 2022 Mar; 23(5). PMID: 35269653
LiCl/pilocarpine status epilepticus (SE) induced in immature rats leads, after a latent period, to hippocampal hyperexcitability. The excitability may be influenced by adenosine, which exhibits anticonvulsant activity. The concentration of...
10.
Kudova E, Mares P, Hill M, Vondrakova K, Tsenov G, Chodounska H, et al.
Pharmaceuticals (Basel) . 2022 Jan; 15(1). PMID: 35056106
Pregnanolone glutamate (PA-G) is a neuroactive steroid that has been previously demonstrated to be a potent neuroprotective compound in several biological models in vivo. Our in vitro experiments identified PA-G...