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Jana Tchekalarova

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Articles 78
Citations 452
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Recent Articles
1.
Tchekalarova J, Atanasova D, Krushovlieva D, Barbutska D, Atanasova M, Rashev P, et al.
Neurochem Int . 2025 Mar; 185:105960. PMID: 40043851
Memory decline is considered a normal part of aging, while the relationship between melatonin deficiency and cognitive function is complex and not fully understood. The present study investigated the role...
2.
Stoyanova T, Nocheva H, Nenchovska Z, Krushovlieva D, Ivanova P, Tchekalarova J
Int J Mol Sci . 2025 Feb; 26(3). PMID: 39940805
Prenatal constant light exposure (CLE) impaired the anxiety response and circadian rhythms of testicular enzymes in adult male rat offspring, while melatonin corrected these deficiencies. However, the mechanism by which...
3.
Georgieva S, Todorov P, Tchekalarova J
Pharmaceuticals (Basel) . 2025 Jan; 18(1). PMID: 39861116
This study explores the potential for the synthesis of peptide nanosystems comprising spinorphin molecules (with rhodamine moiety: Rh-S, Rh-S5, and Rh-S6) conjugated with nanoparticles (AuNPs), specifically peptide Rh-S@AuNPs, peptide Rh-S5@AuNPs,...
4.
Georgieva I, Tchekalarova J, Nenchovska Z, Kortenska L, Tzoneva R
Int J Mol Sci . 2024 Oct; 25(19). PMID: 39408624
In the search for Alzheimer's disease (AD) therapies, most animal models focus on familial AD, which accounts for a small fraction of cases. The majority of AD cases arise from...
5.
Nenchovska Z, Atanasova M, Stoynova T, Toteva G, Tchekalarova J
Physiol Behav . 2024 Oct; 287:114712. PMID: 39393450
In clinical practice, the use of exogenous progesterone (Pro) is often required in assisted reproduction programs due to reduced levels of the hormone and the risk of miscarriage. Exposure to...
6.
Tchekalarova J, Pechlivanova D, Rangelov M, Todorova N, Stoyanova T, Assenov B, et al.
Drug Dev Res . 2024 Jul; 85(5):e22236. PMID: 39032052
The novel cinnamic acid (CA) (H4-CA, H5-CA, and H7-CA) and caffeic acid (KA) (H4-KA, H5-KA, and H7-KA) hemorphin analogs have recently been synthesized and their trans isomers have been tested...
7.
Tchekalarova J, Ivanova P, Krushovlieva D
Int J Mol Sci . 2024 Jul; 25(13). PMID: 39000445
Both hypertension and aging are known to increase the vulnerability of the brain to neurovascular damage, resulting in cognitive impairment. The present study investigated the efficacy of the antihypertensive drug...
8.
Ivanova N, Atanasova M, Terzieva D, Georgieva K, Tchekalarova J
Int J Mol Sci . 2024 Jul; 25(13). PMID: 39000130
Prenatal stress (PNS), which alters the hypothalamic-pituitary-adrenal axis function in the offspring, predisposes to insulin resistance (IR) in later life and is associated with numerous disorders, including cognitive and memory...
9.
Georgieva S, Todorov P, Tchekalarova J, Subaer S, Peneva P, Chakarov K, et al.
Pharmaceuticals (Basel) . 2024 Jun; 17(6). PMID: 38931437
The discovery of new peptides and their derivatives is an outcome of ongoing efforts to identify a peptide with significant biological activity for effective usage as a possible therapeutic agent....
10.
Peshev B, Ivanova P, Krushovlieva D, Kortenska L, Atanasova D, Rashev P, et al.
Int J Mol Sci . 2024 Jun; 25(12). PMID: 38928281
The pivotal role of the basolateral amygdala (BLA) in the emotional modulation of hippocampal plasticity and memory consolidation is well-established. Specifically, multiple studies have demonstrated that the activation of the...