Hamid Nikbakht
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Explore the profile of Hamid Nikbakht including associated specialties, affiliations and a list of published articles.
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20
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1876
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Recent Articles
11.
Mackay A, Burford A, Carvalho D, Izquierdo E, Fazal-Salom J, Taylor K, et al.
Cancer Cell
. 2017 Oct;
32(4):520-537.e5.
PMID: 28966033
We collated data from 157 unpublished cases of pediatric high-grade glioma and diffuse intrinsic pontine glioma and 20 publicly available datasets in an integrated analysis of >1,000 cases. We identified...
12.
Morrissy A, Cavalli F, Remke M, Ramaswamy V, Shih D, Holgado B, et al.
Nat Genet
. 2017 Apr;
49(5):780-788.
PMID: 28394352
Spatial heterogeneity of transcriptional and genetic markers between physically isolated biopsies of a single tumor poses major barriers to the identification of biomarkers and the development of targeted therapies that...
13.
Fiset P, Fontebasso A, De Jay N, Gayden T, Nikbakht H, Majewski J, et al.
Pediatr Blood Cancer
. 2016 Oct;
64(2):275-278.
PMID: 27718322
A cerebellar pilocytic astrocytoma (PA) in a child recurred first with a PA histology and then with features of a ganglioglioma (GG). Molecular genetic analyses of the tumors confirmed a...
14.
Nikbakht H, Panditharatna E, Mikael L, Li R, Gayden T, Osmond M, et al.
Nat Commun
. 2016 Apr;
7:11185.
PMID: 27048880
Diffuse Intrinsic Pontine Gliomas (DIPGs) are deadly paediatric brain tumours where needle biopsies help guide diagnosis and targeted therapies. To address spatial heterogeneity, here we analyse 134 specimens from various...
15.
Nikbakht H, Xia X, Hickey D
Genome
. 2015 Jan;
57(9):507-11.
PMID: 25633864
The genome of the malarial parasite Plasmodium falciparum is extremely AT rich. This bias toward a low GC content is a characteristic of several, but not all, species within the...
16.
Fontebasso A, Gayden T, Nikbakht H, Neirinck M, Papillon-Cavanagh S, Majewski J, et al.
Acta Neuropathol
. 2014 Aug;
128(5):615-27.
PMID: 25077668
A remarkably large number of "epigenetic regulators" have been recently identified to be altered in cancers and a rapidly expanding body of literature points to "epigenetic addiction" (an aberrant epigenetic...
17.
Kahle K, Merner N, Friedel P, Silayeva L, Liang B, Khanna A, et al.
EMBO Rep
. 2014 Jun;
15(7):766-74.
PMID: 24928908
The KCC2 cotransporter establishes the low neuronal Cl(-) levels required for GABAA and glycine (Gly) receptor-mediated inhibition, and KCC2 deficiency in model organisms results in network hyperexcitability. However, no mutations...
18.
Fontebasso A, Papillon-Cavanagh S, Schwartzentruber J, Nikbakht H, Gerges N, Fiset P, et al.
Nat Genet
. 2014 Apr;
46(5):462-6.
PMID: 24705250
Pediatric midline high-grade astrocytomas (mHGAs) are incurable with few treatment targets identified. Most tumors harbor mutations encoding p.Lys27Met in histone H3 variants. In 40 treatment-naive mHGAs, 39 analyzed by whole-exome...
19.
Shokralla S, Gibson J, Nikbakht H, Janzen D, Hallwachs W, Hajibabaei M
Mol Ecol Resour
. 2014 Mar;
14(5):892-901.
PMID: 24641208
DNA barcoding is an efficient method to identify specimens and to detect undescribed/cryptic species. Sanger sequencing of individual specimens is the standard approach in generating large-scale DNA barcode libraries and...
20.
Albu M, Nikbakht H, Hajibabaei M, Hickey D
Mol Ecol Resour
. 2011 Mar;
11(1):84-8.
PMID: 21429103
DNA barcoding is based on the use of short DNA sequences to provide taxonomic tags for rapid, efficient identification of biological specimens. Currently, reference databases are being compiled. In the...