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Halei C Benefield

Explore the profile of Halei C Benefield including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 367
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Recent Articles
1.
Olsson L, Walens A, Hamilton A, Benefield H, Fleming J, Carey L, et al.
Cancer Epidemiol Biomarkers Prev . 2022 Aug; 31(10):1944-1951. PMID: 35973227
Background: Obese women have higher risk of aggressive breast tumors and distant metastasis. However, obesity has rarely been assessed in association with metastasis in diverse populations. Methods: In the Carolina...
2.
Damrauer J, Roell K, Smith M, Sun X, Kirk E, Hoadley K, et al.
Clin Cancer Res . 2021 Jun; 27(16):4599-4609. PMID: 34117034
Purpose: Improved risk stratification and predictive biomarkers of treatment response are needed for non-muscle-invasive bladder cancer (NMIBC). Here we assessed the clinical utility of targeted RNA and DNA molecular profiling...
3.
Emerson M, Achacoso N, Benefield H, Troester M, Habel L
Cancer . 2021 Feb; 127(11):1847-1856. PMID: 33620753
Background: It has been shown that racial/ethnic disparities exist with regard to initiation of and adherence to adjuvant endocrine therapy (AET). However, the relationship among American Indian/Alaska Native (AIAN) individuals...
4.
Benefield H, Reeder-Hayes K, Nichols H, Calhoun B, Love M, Kirk E, et al.
JNCI Cancer Spectr . 2021 Jan; 5(1). PMID: 33442657
Background: Black women have higher hormone receptor positive (HR+) breast cancer mortality than White women. Early recurrence rates differ by race, but little is known about genomic predictors of early...
5.
Benefield H, Zirpoli G, Allott E, Shan Y, Hurson A, Omilian A, et al.
Cancer Epidemiol Biomarkers Prev . 2020 Oct; 30(1):71-79. PMID: 33097496
Background: Evidence suggests etiologic heterogeneity among breast cancer subtypes. Previous studies with six-marker IHC classification of intrinsic subtypes included small numbers of black women. Methods: Using centralized laboratory results for...
6.
Benefield H, Allott E, Reeder-Hayes K, Perou C, Carey L, Geradts J, et al.
J Natl Cancer Inst . 2019 Nov; 112(7):728-736. PMID: 31742342
Background: Some breast tumors expressing greater than 1% and less than 10% estrogen receptor (ER) positivity (ER-borderline) are clinically aggressive; others exhibit luminal biology. Prior ER-borderline studies included few black...
7.
Benefield H, Zabor E, Shan Y, Allott E, Begg C, Troester M
Cancer Epidemiol Biomarkers Prev . 2019 Aug; 28(11):1784-1791. PMID: 31395590
Background: Distinctions in the etiology of triple-negative versus luminal breast cancer have become well established using immunohistochemical surrogates [notably estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor...
8.
OConor C, Ramalingam S, Zelenski N, Benefield H, Rigo I, Little D, et al.
Sci Rep . 2016 Jul; 6:29053. PMID: 27388701
Osteoarthritis (OA) is a progressive degenerative disease of articular cartilage and surrounding tissues, and is associated with both advanced age and joint injury. Biomechanical factors play a critical role in...
9.
OConor C, Leddy H, Benefield H, Liedtke W, Guilak F
Proc Natl Acad Sci U S A . 2014 Jan; 111(4):1316-21. PMID: 24474754
Mechanical loading of joints plays a critical role in maintaining the health and function of articular cartilage. The mechanism(s) of chondrocyte mechanotransduction are not fully understood, but could provide important...