Hailyn V Nielsen
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Explore the profile of Hailyn V Nielsen including associated specialties, affiliations and a list of published articles.
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11
Citations
344
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Recent Articles
1.
Nielsen H, Yang L, Mueller J, Ritter A, Hiwa R, Proekt I, et al.
Nat Commun
. 2025 Jan;
16(1):784.
PMID: 39824797
The Nr4a nuclear hormone receptors are transcriptionally upregulated in response to antigen recognition by the T cell receptor (TCR) in the thymus and are implicated in clonal deletion, but the...
2.
Brooks J, Riggs J, Mueller J, Mathenge R, Wholey W, Meyer A, et al.
Nat Immunol
. 2023 Aug;
24(10):1762-1777.
PMID: 37653247
Multivalent viral epitopes induce rapid, robust and T cell-independent humoral immune responses, but the biochemical basis for such potency remains incompletely understood. We take advantage of a set of liposomes...
3.
Hiwa R, Brooks J, Mueller J, Nielsen H, Zikherman J
Immunol Rev
. 2022 Feb;
307(1):116-133.
PMID: 35174510
Random VDJ recombination early in T and B cell development enables the adaptive immune system to recognize a vast array of evolving pathogens via antigen receptors. However, the potential of...
4.
Hiwa R, Nielsen H, Mueller J, Mandla R, Zikherman J
JCI Insight
. 2021 Aug;
6(17).
PMID: 34343134
The NR4A family of orphan nuclear receptors (Nr4a1-3) plays redundant roles to establish and maintain Treg identity; deletion of multiple family members in the thymus results in Treg deficiency and...
5.
OBrien V, Hannan T, Nielsen H, Hultgren S
Microbiol Spectr
. 2016 Mar;
4(1).
PMID: 26999391
Urinary tract infections (UTI) are among the most common bacterial infections in humans, affecting millions of people every year. UTI cause significant morbidity in women throughout their lifespan, in infant...
6.
Korte-Berwanger M, Sakinc T, Kline K, Nielsen H, Hultgren S, Gatermann S
Infect Immun
. 2013 Oct;
81(12):4525-33.
PMID: 24082071
Staphylococcus saprophyticus is the only species of Staphylococcus that is typically uropathogenic and possesses a gene coding for a D-serine-deaminase (DsdA). As D-serine is prevalent in urine and toxic or...
7.
Nielsen H, Flores-Mireles A, Kau A, Kline K, Pinkner J, Neiers F, et al.
J Bacteriol
. 2013 Aug;
195(19):4484-95.
PMID: 23913319
Enterococci commonly cause hospital-acquired infections, such as infective endocarditis and catheter-associated urinary tract infections. In animal models of these infections, a long hairlike extracellular protein fiber known as the endocarditis-...
8.
Watson Jr M, Nielsen H, Hultgren S, Caparon M
Infect Immun
. 2013 Mar;
81(5):1606-17.
PMID: 23460515
While many virulence factors promoting Streptococcus pyogenes invasive disease have been described, specific streptococcal factors and host properties influencing asymptomatic mucosal carriage remain uncertain. To address the need for a...
9.
Nielsen H, Guiton P, Kline K, Port G, Pinkner J, Neiers F, et al.
mBio
. 2012 Jul;
3(4):e00177-12.
PMID: 22829678
Unlabelled: Though the bacterial opportunist Enterococcus faecalis causes a myriad of hospital-acquired infections (HAIs), including catheter-associated urinary tract infections (CAUTIs), little is known about the virulence mechanisms that it employs....
10.
Maddalo G, Chovanec P, Stenberg-Bruzell F, Nielsen H, Jensen-Seaman M, Ilag L, et al.
Proteomics
. 2011 Jul;
11(19):3935-41.
PMID: 21800426
Enterococcus faecalis is a gram-positive bacterium that is part of the indigenous microbiotica of humans and animals as well as an opportunistic pathogen. In this study, we have fractionated the...