Hailian Shen
Overview
Explore the profile of Hailian Shen including associated specialties, affiliations and a list of published articles.
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13
Citations
217
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0
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Recent Articles
1.
Liu J, Liu Y, Shao J, Li Y, Qin L, Shen H, et al.
Cell Death Differ
. 2019 Mar;
26(11):2479-2492.
PMID: 30858607
During neocortical development, there are two important events, including expansion of the neural progenitor pool through symmetric divisions, and generation of neurons via asymmetrical divisions that lead to a serial...
2.
Park M, Shen H, Kim N, Gao F, Failor C, Knudtson J, et al.
J Clin Endocrinol Metab
. 2018 Aug;
103(11):4283-4292.
PMID: 30099503
Context: Mutations in the gene encoding Mediator complex subunit MED12 are dominant drivers of uterine fibroids (UFs) in women of diverse racial and ethnic origins. Previously, we showed that UF-linked...
3.
Park M, Shen H, Spaeth J, Tolvanen J, Failor C, Knudtson J, et al.
J Biol Chem
. 2018 Feb;
293(13):4870-4882.
PMID: 29440396
Somatic mutations in exon 2 of the RNA polymerase II transcriptional Mediator subunit occur at high frequency in uterine fibroids (UFs) and breast fibroepithelial tumors as well as recurrently, albeit...
4.
Villalon E, Dale J, Jones M, Shen H, Garcia M
Brain Res
. 2015 Oct;
1627:143-53.
PMID: 26423936
Charcot-Marie-Tooth disease (CMT) is the most commonly inherited peripheral neuropathy. CMT disease signs include distal limb neuropathy, abnormal gait, sensory defects, and deafness. We generated a novel line of CMT2E...
5.
Luo H, Wu H, Shen H, Chen H, Yang T, Huang Z, et al.
Eur Arch Otorhinolaryngol
. 2015 Jul;
273(7):1677-87.
PMID: 26187738
This study aimed to test the association between the European GWAS-identified risk IQGAP2 SNP rs457717 (A>G) and age-related hearing impairment (ARHI) in a Han male Chinese (HMC) population. A total...
6.
Liu T, Zhang T, Yu H, Shen H, Xia W
J Neuroinflammation
. 2014 Jun;
11:107.
PMID: 24927761
Neuroinflammation mediated by activation of microglia and interruption of the blood-brain barrier (BBB) is an important factor that contributes to neuron death and infarct area diffusion in ischemia reperfusion injury....
7.
Dale J, Shen H, Barry D, Garcia V, Rose Jr F, Lorson C, et al.
Acta Neuropathol
. 2011 Jun;
122(3):331-41.
PMID: 21681521
Spinal muscular atrophy (SMA) is a neurodegenerative disease resulting from decreased levels of survival motor neuron 1 (SMN1) protein. Reduced SMN1 levels are linked to pathology at neuromuscular junctions (NMJs),...
8.
Shen H, Barry D, Dale J, Garcia V, Calcutt N, Garcia M
Hum Mol Genet
. 2011 Apr;
20(13):2535-48.
PMID: 21493625
Mutations in neurofilament light (NF-L) have been linked to Charcot-Marie-Tooth disease type 2E (CMT2E) in humans. To provide insight into disease pathogenesis, we developed a novel line of CMT2E mice...
9.
Niu Z, Shen A, Shen H, Jiang J, Zong H, Gu J
Mol Cell Biochem
. 2005 Mar;
270(1-2):99-106.
PMID: 15792358
Protein kinases are important signalling molecules critical for normal cell growth and development. CDK11(p58) is a p34(cdc2) related protein kinase, and plays an important role in normal cell cycle progression....
10.
Wang H, Shen H, Wang Y, Li Z, Yin H, Zong H, et al.
FEBS Lett
. 2005 Feb;
579(5):1279-84.
PMID: 15710426
It is known that small glutamine-rich TPR-containing protein (SGT) is the member of TPR motif family. However, the biological functions of SGT remain unclear. In this paper, we report that...