Haichang Huang
Overview
Explore the profile of Haichang Huang including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
232
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Recent Articles
1.
Wang C, Huang H, Mallon K, Valera L, Parcella K, Cockett M, et al.
Antimicrob Agents Chemother
. 2023 Apr;
67(5):e0169422.
PMID: 37039636
GSK878 is a newly described HIV-1 inhibitor that binds to the mature capsid (CA) hexamer in a pocket originally identified as the binding site of the well-studied CA inhibitor PF-74....
2.
Gillis E, Parcella K, Bowsher M, Cook J, Iwuagwu C, Naidu B, et al.
J Med Chem
. 2023 Jan;
66(3):1941-1954.
PMID: 36719971
Long-acting (LA) human immunodeficiency virus-1 (HIV-1) antiretroviral therapy characterized by a ≥1 month dosing interval offers significant advantages over daily oral therapy. However, the criteria for compounds that enter clinical...
3.
Li Y, Liu X, Wang W, Wang S, Zhang J, Jiang S, et al.
Ren Fail
. 2018 Apr;
40(1):280-288.
PMID: 29619880
Background: Patients with chronic kidney disease (CKD) often have CD4+ regulatory T cells (Tregs) dysfunction and chronic inflammation. We aim to investigate the effect, function, and related mechanism of low-dose...
4.
Liu X, Wang W, Li J, Li Y, Li L, Wang S, et al.
Cell Physiol Biochem
. 2016 Jan;
38(1):401-14.
PMID: 26824459
Background/aims: Indoxyl sulfate, an important protein-bound uremic toxin, can damage stem cells, thus hampering stem cell-based regenerative medicine approaches targeting chronic kidney diseases (CKD). Human umbilical cord-derived mesenchymal stem cells...
5.
Wan M, Gu H, Wang J, Huang H, Zhao J, Kaundal R, et al.
Development
. 2013 Jan;
140(4):843-52.
PMID: 23325759
Environmental factors can stably perturb the epigenome of exposed individuals and even that of their offspring, but the pleiotropic effects of these factors have posed a challenge for understanding the...
6.
Chaiyachati B, Jani A, Wan Y, Huang H, Flavell R, Chi T
EMBO J
. 2013 Jan;
32(3):395-408.
PMID: 23321680
Treg activation in response to environmental cues is necessary for regulatory T cells (Tregs) to suppress inflammation, but little is known about the transcription mechanisms controlling Treg activation. We report...
7.
Wan M, Kaundal R, Huang H, Zhao J, Yang X, Chaiyachati B, et al.
J Immunol
. 2013 Jan;
190(2):737-47.
PMID: 23293358
Synthetic regulatory proteins such as tetracycline (tet)-controlled transcription factors are potentially useful for repression as well as ectopic activation of endogenous genes and also for probing their regulatory mechanisms, which...
8.
Wang C, Huang H, Valera L, Sun J, OBoyle 2nd D, Nower P, et al.
Antimicrob Agents Chemother
. 2012 Jan;
56(3):1350-8.
PMID: 22214777
BMS-790052, a first-in-class hepatitis C virus (HCV) replication complex inhibitor, targeting nonstructural protein 5A (NS5A), displays picomolar to nanomolar potency against genotypes 1 to 5. This exceptional potency translated into...
9.
Wang C, Jia L, Huang H, Qiu D, Valera L, Huang X, et al.
Antimicrob Agents Chemother
. 2011 Dec;
56(3):1588-90.
PMID: 22203595
The antiviral profile of BMS-790052, a potent hepatitis C virus (HCV) replication complex inhibitor targeting nonstructural protein NS5A, is well characterized for HCV genotype-1. Here, we report that BMS-790052 inhibits...
10.
Gao X, Li J, Huang H, Li X
Wound Repair Regen
. 2008 May;
16(3):408-15.
PMID: 18471259
Myofibroblasts primarily contribute to the pathogenesis of renal interstitial fibrosis by unregulated cell proliferation and synthesis of excessive amounts of extracellular matrix (ECM) proteins. We used cultured myofibroblast-like cells obtained...