Hai Xia Zhang
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Explore the profile of Hai Xia Zhang including associated specialties, affiliations and a list of published articles.
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9
Citations
161
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Recent Articles
1.
Zhang H, Liu O, Deng C, He Y, Feng Y, Ma J, et al.
Clin Oral Investig
. 2017 Mar;
22(1):209-216.
PMID: 28357642
Objective: Tongue squamous cell carcinoma (TSCC) is significantly more malignant than other type of oral squamous cell carcinoma (OSCC). In this study, we aimed to identify specific global gene expression...
2.
Levin M, Singh G, Zhang H, Uchida K, Kozel B, Stein P, et al.
Proc Natl Acad Sci U S A
. 2016 Jun;
113(24):6773-8.
PMID: 27247394
Cantu syndrome (CS) is caused by gain-of-function (GOF) mutations in genes encoding pore-forming (Kir6.1, KCNJ8) and accessory (SUR2, ABCC9) KATP channel subunits. We show that patients with CS, as well...
3.
Zhang H, Silva J, Lin Y, Verbsky J, Lee U, Kanter E, et al.
Heart Rhythm
. 2013 Jul;
10(10):1576-83.
PMID: 23871704
Background: The concept that pore-forming Kir6.2 and regulatory SUR2A subunits form cardiac ATP-sensitive potassium (K(ATP)) channels is challenged by recent reports that SUR1 is predominant in mouse atrial K(ATP) channels....
4.
Toib A, Zhang H, Broekelmann T, Hyrc K, Guo Q, Chen F, et al.
J Mol Cell Cardiol
. 2012 Jul;
53(3):437-45.
PMID: 22796573
Transgenic mice overexpressing SUR1 and gain of function Kir6.2[∆N30, K185Q] K(ATP) channel subunits, under cardiac α-myosin heavy chain (αMHC) promoter control, demonstrate arrhythmia susceptibility and premature death. Pregnant mice, crossed...
5.
Zhang H, Akrouh A, Kurata H, Remedi M, Lawton J, Nichols C
J Mol Cell Cardiol
. 2010 Dec;
50(3):552-60.
PMID: 21185839
Murine ventricular and atrial ATP-sensitive potassium (K(ATP)) channels contain different sulfonylurea receptors (ventricular K(ATP) channels are Kir6.2/SUR2A complexes, while atrial K(ATP) channels are Kir6.2/SUR1 complexes). HMR 1098, the sodium salt...
6.
Zhang H, Lyons-Warren A, Thio L
Neuropharmacology
. 2009 Jul;
57(5-6):551-5.
PMID: 19619564
Sarcosine is an endogenous amino acid that is a competitive inhibitor of the type I glycine transporter (GlyT1), an N-methyl-d-aspartate receptor (NMDAR) co-agonist, and an important intermediate in one-carbon metabolism....
7.
Zhang H, Hyrc K, Thio L
J Physiol
. 2009 May;
587(Pt 13):3207-20.
PMID: 19433577
Sarcosine is an amino acid involved in one-carbon metabolism and a promising therapy for schizophrenia because it enhances NMDA receptor (NMDAR) function by inhibiting glycine uptake. The structural similarity between...
8.
Xu L, Rensing N, Yang X, Zhang H, Thio L, Rothman S, et al.
J Clin Invest
. 2007 Dec;
118(1):272-80.
PMID: 18097472
Leptin is a hormone that reduces excitability in some hypothalamic neurons via leptin receptor activation of the JAK2 and PI3K intracellular signaling pathways. We hypothesized that leptin receptor activation in...
9.
Zhang H, Thio L
J Neurophysiol
. 2007 Oct;
98(6):3666-76.
PMID: 17913992
Although extracellular Zn(2+) is an endogenous biphasic modulator of strychnine-sensitive glycine receptors (GlyRs), the physiological significance of this modulation remains poorly understood. Zn(2+) modulation of GlyR may be especially important...