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Hahn Nahmgoong

Explore the profile of Hahn Nahmgoong including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 169
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Recent Articles
1.
Han S, Nahmgoong H, Yim K, Kim J
Trends Endocrinol Metab . 2024 Aug; 36(2):147-160. PMID: 39095230
Cellular turnover is fundamental for tissue homeostasis and integrity. Adipocyte turnover, accounting for 4% of the total cellular mass turnover in humans, is essential for adipose tissue homeostasis during metabolic...
2.
Choi S, Kang J, Tran Y, Jeong S, Park K, Shin H, et al.
Nat Metab . 2024 May; 6(5):847-860. PMID: 38811804
Adipose tissues serve as an energy reservoir and endocrine organ, yet the mechanisms that coordinate these functions remain elusive. Here, we show that the transcriptional coregulators, YAP and TAZ, uncouple...
3.
Jeon Y, Nahmgoong H, Oh J, Lee D, Kim D, Kim J, et al.
Nat Commun . 2024 Jan; 15(1):940. PMID: 38296968
In mammals, brown adipose tissue (BAT) and inguinal white adipose tissue (iWAT) execute sequential thermogenesis to maintain body temperature during cold stimuli. BAT rapidly generates heat through brown adipocyte activation,...
4.
Han S, Park E, Park J, Nahmgoong H, Choi Y, Oh J, et al.
Nat Commun . 2023 Dec; 14(1):8512. PMID: 38129377
Adipose tissue invariant natural killer T (iNKT) cells are a crucial cell type for adipose tissue homeostasis in obese animals. However, heterogeneity of adipose iNKT cells and their function in...
5.
Shin K, Huh J, Ji Y, Han J, Han S, Park J, et al.
Cell Rep . 2022 Dec; 41(11):111806. PMID: 36516764
In mammals, brown adipose tissue (BAT) is specialized to conduct non-shivering thermogenesis for survival under cold acclimation. Although emerging evidence suggests that lipid metabolites are essential for heat generation in...
6.
Han J, Jeon Y, Oh M, Lee G, Nahmgoong H, Han S, et al.
Nat Commun . 2022 Jun; 13(1):3268. PMID: 35672324
Thermogenic adipocytes generate heat to maintain body temperature against hypothermia in response to cold. Although tight regulation of thermogenesis is required to prevent energy sources depletion, the molecular details that...
7.
Kim Y, Jang H, Lee G, Jeon Y, Sohn J, Han J, et al.
Diabetes . 2022 Apr; 71(7):1373-1387. PMID: 35476750
Excessive hepatic glucose production (HGP) is a key factor promoting hyperglycemia in diabetes. Hepatic cryptochrome 1 (CRY1) plays an important role in maintaining glucose homeostasis by suppressing forkhead box O1...
8.
Lee G, Kim Y, Jang H, Han J, Nahmgoong H, Park Y, et al.
Cell Metab . 2022 Apr; 34(5):702-718.e5. PMID: 35417665
Emerging evidence indicates that the accretion of senescent cells is linked to metabolic disorders. However, the underlying mechanisms and metabolic consequences of cellular senescence in obesity remain obscure. In this...
9.
Nahmgoong H, Jeon Y, Park E, Choi Y, Han S, Park J, et al.
Cell Metab . 2022 Jan; 34(3):458-472.e6. PMID: 35021043
In mammals, white adipose tissues are largely divided into visceral epididymal adipose tissue (EAT) and subcutaneous inguinal adipose tissue (IAT) with distinct metabolic properties. Although emerging evidence suggests that subpopulations...
10.
Sohn J, Ji Y, Cho C, Nahmgoong H, Lim S, Jeon Y, et al.
Diabetes . 2021 Sep; 70(12):2756-2770. PMID: 34521642
Reactive oxygen species (ROS) are associated with various roles of brown adipocytes. Glucose-6-phosphate dehydrogenase (G6PD) controls cellular redox potentials by producing NADPH. Although G6PD upregulates cellular ROS levels in white...