Hagit Eliyahu
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Explore the profile of Hagit Eliyahu including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
98
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Recent Articles
1.
Even-Or O, Joseph A, Itskovitz-Cooper N, Samira S, Rochlin E, Eliyahu H, et al.
Vaccine
. 2011 Jan;
29(13):2474-86.
PMID: 21251901
We recently showed that lipid assemblies comprised of a novel polycationic sphingolipid (ceramide carbamoyl-spermine, CCS) are an effective adjuvant/carrier when complexed with cholesterol (CCS/C) for influenza and other vaccines administered...
2.
Yudovin-Farber I, Eliyahu H, Domb A
Cold Spring Harb Protoc
. 2011 Jan;
2011(1):pdb.prot5553.
PMID: 21205853
Polycations are effective nonviral carriers for gene delivery systems. These carriers vary in molecular weight, polymer structure, polymer:DNA ratio, molecular architecture, and the ability to introduce target-specific moieties. Polycations are...
3.
Joseph A, Itskovitz-Cooper N, Samira S, Flasterstein O, Eliyahu H, Simberg D, et al.
Vaccine
. 2006 Mar;
24(18):3990-4006.
PMID: 16516356
Although most pathogens use the mucosal routes for invasion, the majority of currently available vaccines are administered parenterally. Injectable vaccines induce good systemic immunity but often unsatisfactory mucosal immunity. A...
4.
Eliyahu H, Siani S, Azzam T, Domb A, Barenholz Y
Biomaterials
. 2005 Oct;
27(8):1646-55.
PMID: 16242185
Biodegradable water-soluble polysaccharide-spermine (SPM) polycation conjugates for nucleic acid delivery were synthesized by oxidizing polysaccharides using potassium periodate, followed by SPM conjugation. The polycations differ in their polysaccharide type, arabinogalactan...
5.
Eliyahu H, Joseph A, Azzam T, Barenholz Y, Domb A
Biomaterials
. 2005 Oct;
27(8):1636-45.
PMID: 16221492
Gene delivery using self-assembled polyplexes, formed between negatively charged nucleic acids and cationic polymers, have several drawbacks including low transgene expression and toxicity effects related to their positive charge. Recently,...
6.
Hirsch-Lerner D, Zhang M, Eliyahu H, Ferrari M, Wheeler C, Barenholz Y
Biochim Biophys Acta
. 2005 Jul;
1714(2):71-84.
PMID: 16051183
Lipoplexes, which are complexes between cationic liposomes (L+) and nucleic acids, are commonly used as a nucleic acid delivery system in vitro and in vivo. This study aimed to better...
7.
Azzam T, Eliyahu H, Makovitzki A, Linial M, Domb A
J Control Release
. 2004 Apr;
96(2):309-23.
PMID: 15081221
Dextran polysaccharide was grafted by reductive-amination with mixtures of spermine and other natural/synthetic oligoamines of two to four amine groups. The transfection efficiencies of the polycations thus obtained were assessed...
8.
Azzam T, Eliyahu H, Shapira L, Linial M, Barenholz Y, Domb A
J Med Chem
. 2002 Apr;
45(9):1817-24.
PMID: 11960493
This work describes a versatile and universal polycation system based on oligoamines grafted on natural polysaccharides that is capable of complexing various plasmids and administering them into various cells in...