Hagen S Bachmann
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Explore the profile of Hagen S Bachmann including associated specialties, affiliations and a list of published articles.
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43
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605
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Recent Articles
1.
Diehl D, Brauer C, Bachmann H, Pembaur D, Weil P, Friedmann A
Clin Exp Dent Res
. 2025 Feb;
11(1):e70099.
PMID: 39967042
Objectives: Periodontitis is a prevalent inflammatory disease with established systemic implications. Extracellular vesicles (EVs) have emerged as key mediators of intercellular communication, potentially linking periodontitis to systemic diseases. However, the...
2.
Stegen M, Bachmann H, Belani G, Mohamed A, Breuing B, Brenner T, et al.
Eur J Anaesthesiol Intensive Care
. 2025 Feb;
3(4):e0056.
PMID: 39917251
Background: Postoperative nausea and vomiting (PONV) are the most frequent complications in the context of anaesthesia. Several studies suggest a contribution of genetic traits to PONV disposition. Single nucleotide polymorphisms...
3.
Xu S, Dolff S, Mulling N, Bachmann H, Dai Y, Lindemann M, et al.
Front Transplant
. 2024 Jul;
2:1233322.
PMID: 38993912
Objectives: Farnesyltransferase inhibitors (FTI), which inhibit the prenylation of Ras GTPases, were developed as anti-cancer drugs. As additional target proteins for prenylation were identified in the past, it is likely...
4.
Diehl D, Friedmann A, Bachmann H
J Periodontol
. 2023 Jul;
94(12):1450-1460.
PMID: 37432945
Background: Prenyltrasferases (PTases) are a class of enzymes known to be responsible for promoting posttranslational modification at the carboxyl terminus of proteins containing a so-called CaaX-motif. The process is responsible...
5.
Jung D, Bachmann H
Biomed Pharmacother
. 2023 May;
164:114915.
PMID: 37236024
Prenyltransferases (PTases) are known to play a role in embryonic development, normal tissue homeostasis and cancer by posttranslationally modifying proteins involved in these processes. They are being discussed as potential...
6.
Kehrenberg M, Bachmann H
Naunyn Schmiedebergs Arch Pharmacol
. 2022 Mar;
395(6):619-627.
PMID: 35294605
Diuretics are drugs that increase the flow of urine. They are commonly used to treat edema, hypertension, and heart failure. Typically, the pharmacological group consists of five classes: thiazide diuretics,...
7.
Verhasselt H, Stelmach P, Domin M, Jung D, Hagemann A, Manthey I, et al.
Genomics
. 2022 Feb;
114(2):110314.
PMID: 35167937
Farnesyltransferase (FTase) enables about 100 proteins to interact with cellular membranes by catalyzing the posttranslational addition of a farnesyl group. Farnesylated proteins provide important functions and inhibitors against the β-subunit...
8.
Diehl D, Friedmann A, Bachmann H
Clin Exp Dent Res
. 2022 Feb;
8(2):473-484.
PMID: 35106960
Objective: To underline the necessity of adequate reference genes for real-time quantitative polymerase chain reaction (RT-qPCR) and evaluate a novel tool for condition-specific reference gene selection. Background: RT-qPCR is a...
9.
Bussing A, Lindeberg A, Stock-Schroer B, Martin D, Scheffer C, Bachmann H
Front Psychiatry
. 2022 Jan;
12:768341.
PMID: 35058817
During the first lockdown of the COVID-19 pandemic, several medical students volunteered as assistants in hospitals, public health departments, and other healthcare services to support and substitute permanent staff. The...
10.
Mese K, Bunz O, Volkwein W, Vemulapalli S, Zhang W, Schellhorn S, et al.
Int J Mol Sci
. 2021 Sep;
22(18).
PMID: 34576237
Previous studies reported on the broad-spectrum antiviral function of heparin. Here we investigated the antiviral function of magnesium-modified heparin and found that modified heparin displayed a significantly enhanced antiviral function...