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H Wolburg

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Articles 145
Citations 3072
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Recent Articles
1.
Hulper P, Veszelka S, Walter F, Wolburg H, Fallier-Becker P, Piontek J, et al.
Br J Pharmacol . 2013 Apr; 169(7):1561-73. PMID: 23617601
Background And Purpose: The blood-brain barrier (BBB) restricts drug penetration to the brain preventing effective treatment of patients suffering from brain tumours. Intra-arterial injection of short-chain alkylglycerols (AGs) opens the...
2.
Hirt B, Gleiser C, Eckhard A, Mack A, Muller M, Wolburg H, et al.
Neuroscience . 2011 May; 189:79-92. PMID: 21621589
The water channel aquaporin-4 (AQP4) is expressed in the cochlea and is essential for normal hearing. Unlike other AQPs, multiple isoforms of AQP4 have been reported in diverse tissues, three...
3.
Dejana E, Simionescu M, Wolburg H
Cell Tissue Res . 2008 Nov; 335(1):1-3. PMID: 19015887
No abstract available.
4.
Zirn B, Grundmann K, Huppke P, Puthenparampil J, Wolburg H, Riess O, et al.
J Neurol Neurosurg Psychiatry . 2008 May; 79(12):1327-30. PMID: 18477710
Background: The three-nucleotide deletion, triangle upGAG (within the gene TOR1A), is the only proven cause of childhood-onset dystonia (DYT1). A potentially pathogenic role of additional sequence changes within TOR1A has...
5.
Kannenberg K, Wittekindt N, Tippmann S, Wolburg H, Ranke M, Binder G
J Neuroendocrinol . 2007 Oct; 19(11):882-90. PMID: 17927666
Autosomal dominant isolated growth hormone deficiency type II (IGHD II) is mainly caused by splice site mutations of the GH-1 gene, leading to deletion of amino acids 32-71 of the...
6.
Grundmann K, Reischmann B, Vanhoutte G, Hubener J, Teismann P, Hauser T, et al.
Neurobiol Dis . 2007 Jul; 27(2):190-206. PMID: 17601741
Primary torsion dystonia is an autosomal-dominant inherited movement disorder. Most cases are caused by an in-frame deletion (GAG) of the DYT1 gene encoding torsinA. Reduced penetrance and phenotypic variability suggest...
7.
Naumann U, Bahr O, Wolburg H, Altenberend S, Wick W, Liston P, et al.
Gene Ther . 2006 Sep; 14(2):147-61. PMID: 16957768
The expression of inhibitor of apoptosis (IAP) family members contributes to the resistance of human cancers to apoptosis induced by radiotherapy and chemotherapy. We report that the infection of malignant...
8.
Naumann U, Huang H, Wolburg H, Wischhusen J, Weit S, Ohgaki H, et al.
Cancer Gene Ther . 2005 Nov; 13(5):469-78. PMID: 16276348
Chimeric tumor suppressor-1 (CTS-1) is based on the sequence of p53 and was designed as a therapeutic tool resisting various mechanisms of p53 inactivation. We previously reported that an adenovirus...
9.
Hoffmann J, Feng Y, vom Hagen F, Hillenbrand A, Lin J, Erber R, et al.
FASEB J . 2005 Oct; 19(14):2035-6. PMID: 16215210
Pericyte loss and capillary regression are characteristic for incipient diabetic retinopathy. Pericyte recruitment is involved in vessel maturation, and ligand-receptor systems contributing to pericyte recruitment are survival factors for endothelial...
10.
Naumann U, Wischhusen J, Weit S, Rieger J, Wolburg H, Massing U, et al.
Cell Death Differ . 2004 Sep; 11(12):1326-41. PMID: 15389288
Alkylphosphocholines (APC) are candidate anticancer agents. We here report that APC induce the formation of large vacuoles and typical features of apoptosis in human glioma cell lines, but not in...